Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29014857 | 0.86 | TDP1 (0.41) | TSHRCYP2D6CYP2C19HIF1ATDP1 | |
| SCHEMBL5675707 | 0.82 | TDP1 (0.48) | TSHRTDP1FFAR1CPT2ALDH1A1 | |
| SCHEMBL2276513 | 0.77 | LMNA (0.40) | TSHRCYP2D6CYP2C19HIF1AHMGCR | |
| SCHEMBL28974561 | 0.75 | KDM4E (0.39) | TSHRCYP2D6CYP2C19HIF1AHMGCR | |
| SCHEMBL1604002 | 0.74 | HMGCR (0.43) | TSHRCYP2D6CYP2C19HIF1AHMGCR | |
| SCHEMBL2233437 | 0.73 | CYP2C19 (0.68) | TSHRCYP2D6CYP2C19HIF1AHMGCR | |
| SCHEMBL11819410 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1ESR1ALOX15 | |
| SCHEMBL4742763 | 0.72 | HMGCR (0.48) | TSHRCYP2D6CYP2C19HIF1AHMGCR | |
| SCHEMBL974936 | 0.72 | FFAR1 (0.65) | TSHRCYP2D6CYP2C19HIF1AHMGCR | |
| SCHEMBL380973 | 0.72 | HMGCR (0.48) | TSHRCYP2D6CYP2C19HIF1AHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740086-A1 | METHOD FOR PRODUCING AROMA SUBSTANCES WITH AN IMPROVED SENSORY PROFILE | Symrise AG (DE) | 2020-11-25 | — | — | EP | disclosed |
| WO-2019141358-A1 | METHOD FOR PRODUCING AROMA SUBSTANCES WITH AN IMPROVED SENSORY PROFILE | SYMRISE AG (DE) | 2019-07-25 | — | — | WO | disclosed |
| US-7589070-B2 | Surface modification for improving biocompatibility | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2009-09-15 | — | — | US | disclosed |
| US-20030044408-A1 | Surface modification for improving biocompatibility | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 2003-03-06 | — | — | US | disclosed |
| WO-2002103004-A1 | SURFACE MODIFICATION FOR IMPROVING BIOCOMPATIBILITY | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2002-12-27 | — | — | WO | disclosed |
| US-20020115819-A1 | Polymerizable compositions for manufacturing transparent polymeric substrates, resulting transparent polymeric substrates and their applications in the optical field | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2002-08-22 | — | — | US | disclosed |