Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228778 | 0.89 | CHRM1 (0.43) | CHRM1ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL4236355 | 0.84 | CHRM1 (0.43) | CHRM1ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL4236228 | 0.84 | SIGMAR1 (0.50) | CHRM1ADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL4230418 | 0.80 | CHRM1 (0.51) | CHRM1 | |
| SCHEMBL4049143 | 0.76 | CHRM1 (0.35) | CHRM1ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL4222239 | 0.74 | CHRM1 (0.41) | CHRM1ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL4051360 | 0.68 | SIGMAR1 (0.47) | CHRM1ADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL4231625 | 0.66 | CHRM1 (0.53) | CHRM1 | |
| SCHEMBL4049616 | 0.66 | SIGMAR1 (0.49) | CHRM1ADRA1AADRA1BDRD2HTR2A | |
| SCHEMBL8012302 | 0.63 | CHRM1 (0.53) | CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106534-A1 | NOVEL HETEROCYCLIC CARBOXAMIDES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |