Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.47 |
| ▸ | BRAF | P15056 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | ARAF | P10398 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236682 | 0.99 | PKM (0.64) | PKMTAS1R3TAS1R1MTNR1BBRAF | |
| SCHEMBL4228568 | 0.86 | MAPK1 (0.50) | PKMMTNR1BBRAFHDAC1RAF1 | |
| SCHEMBL4233255 | 0.84 | PKM (0.59) | PKMTAS1R3TAS1R1MTNR1BBRAF | |
| SCHEMBL4229275 | 0.82 | PKM (0.63) | PKMTAS1R3TAS1R1MTNR1BCYP2C9 | |
| SCHEMBL4227928 | 0.81 | PKM (0.69) | PKMTAS1R3TAS1R1MTNR1BCYP2C9 | |
| SCHEMBL12593832 | 0.81 | AAK1 (0.48) | TAS1R3TAS1R1MTNR1BBRAFHDAC1 | |
| SCHEMBL4788024 | 0.81 | PKM (0.59) | PKMTAS1R3TAS1R1MTNR1BRAF1 | |
| SCHEMBL4689054 | 0.81 | TAS1R3 (0.72) | PKMTAS1R3TAS1R1MTNR1BRAF1 | |
| Ammonia Solution, Strong SCHEMBL4235457 | 0.81 | PKM (0.58) | PKMTAS1R3TAS1R1MTNR1BALDH1A1 | |
| SCHEMBL4235362 | 0.80 | TAS1R3 (0.46) | PKMTAS1R3TAS1R1MTNR1BBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | PKM 1734/4885TAS1R3 1436/4885TAS1R1 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.