Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MYOC | Q99972 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233933 | 0.88 | RAF1 (0.49) | POLBRAF1MAPTMEN1KMT2A | |
| SCHEMBL4236682 | 0.82 | PKM (0.64) | PKMTAS1R3TAS1R1RAF1MAPK1 | |
| SCHEMBL4785954 | 0.82 | KMT2A (0.70) | PKMHTTPOLBMAPTMEN1 | |
| SCHEMBL4690580 | 0.82 | MEN1 (0.49) | HTTPOLBRAF1MAPTMEN1 | |
| Ammonia Solution, Strong SCHEMBL4235357 | 0.81 | PKM (0.63) | PKMTAS1R3TAS1R1RAF1MAPK1 | |
| SCHEMBL4788031 | 0.81 | KDR (0.52) | HTTRAF1MAPTMEN1KMT2A | |
| SCHEMBL4787992 | 0.80 | KMT2A (0.55) | PKMTAS1R3TAS1R1HTTPOLB | |
| SCHEMBL4232078 | 0.80 | KMT2A (0.55) | PKMTAS1R3TAS1R1HTTPOLB | |
| SCHEMBL4689054 | 0.78 | TAS1R3 (0.72) | PKMTAS1R3TAS1R1HTTPOLB | |
| SCHEMBL4236591 | 0.77 | PKM (0.53) | PKMTAS1R3TAS1R1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |