Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 2/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16511543 | 0.87 | SCN5A (0.72) | SCN5ASIGMAR1HRH3HRH1LTA4H | |
| SCHEMBL22386773 | 0.86 | LTA4H (0.59) | SIGMAR1HRH3HRH1KCNH2LTA4H | |
| SCHEMBL2741684 | 0.86 | LTA4H (0.59) | SIGMAR1HRH3HRH1KCNH2LTA4H | |
| SCHEMBL16511226 | 0.85 | SCN5A (0.69) | SCN5ASIGMAR1HRH3HRH1LTA4H | |
| Hydrochloric Acid SCHEMBL227403 | 0.84 | LTA4H (0.58) | SIGMAR1HRH3HRH1KCNH2LTA4H | |
| SCHEMBL4767153 | 0.83 | SIGMAR1 (0.63) | SIGMAR1HRH3MAPTHDAC1HRH1 | |
| Hydrochloric Acid SCHEMBL6596661 | 0.83 | LTA4H (0.59) | SIGMAR1HRH3HRH1KCNH2LTA4H | |
| SCHEMBL9866577 | 0.83 | SIGMAR1 (0.79) | SCN5ASIGMAR1HRH3LTA4H | |
| SCHEMBL7031548 | 0.82 | HRH3 (0.62) | SIGMAR1HRH3KCNH2 | |
| SCHEMBL2741683 | 0.82 | HRH3 (0.62) | SIGMAR1HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | SCN5A 499/4885SIGMAR1 303/4885HRH3 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.