Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.79 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810029 | 0.94 | SIGMAR1 (0.71) | SIGMAR1SCN5ASLC6A3LTA4HHRH3 | |
| SCHEMBL16511543 | 0.92 | SCN5A (0.72) | SIGMAR1SCN5ALTA4HHRH3 | |
| SCHEMBL16511226 | 0.90 | SCN5A (0.69) | SIGMAR1SCN5ASLC6A3LTA4HHRH3 | |
| SCHEMBL5708589 | 0.89 | SIGMAR1 (0.73) | SIGMAR1LTA4H | |
| Hydrochloric Acid SCHEMBL5756391 | 0.89 | SIGMAR1 (0.93) | SIGMAR1SLC6A3LTA4HHRH3DPP7 | |
| SCHEMBL9019137 | 0.88 | SIGMAR1 (1.00) | SIGMAR1SLC6A3LTA4HDPP7 | |
| SCHEMBL13661556 | 0.87 | SIGMAR1 (0.79) | SIGMAR1SCN5ASLC6A3LTA4HHRH3 | |
| Hydrochloric Acid SCHEMBL10606789 | 0.84 | DPP7 (0.76) | SIGMAR1SCN5ASLC6A3LTA4HHRH3 | |
| SCHEMBL4236303 | 0.83 | SCN5A (0.58) | SIGMAR1SCN5ALTA4HHRH3 | |
| SCHEMBL83687 | 0.83 | SIGMAR1 (0.86) | SIGMAR1SLC6A3LTA4HHRH3GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |