⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5443341 | 0.67 | — | — | |
| SCHEMBL4698157 | 0.67 | — | — | |
| SCHEMBL8158051 | 0.67 | — | — | |
| SCHEMBL1491907 | 0.59 | — | — | |
| SCHEMBL16197017 | 0.58 | NR1I2 (0.31) | — | |
| Water SCHEMBL6096372 | 0.57 | MGLL (0.42) | — | |
| SCHEMBL1721131 | 0.55 | — | — | |
| SCHEMBL8724660 | 0.51 | — | — | |
| SCHEMBL7771362 | 0.50 | — | — | |
| SCHEMBL10767319 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948241-B1 | MULTI-DRUG LIGAND CONJUGATES | ENDOCYTE INC (US) | 2014-03-05 | — | — | EP | claimed |
| US-7601332-B2 | Minimized toxicity; eliminating pathogenic cell populations; synthesis; claimed intermediates | ENDOCYTE, INC. (US) | 2009-10-13 | — | — | US | claimed |
| US-20080248052-A1 | Vitamin receptor binding drug delivery conjugate | ENDOCYTE, INC. | 2008-10-09 | — | — | US | claimed |
| EP-1948241-A2 | MULTI-DRUG LIGAND CONJUGATES | Endocyte, Inc. (US) | 2008-07-30 | — | — | EP | claimed |
| WO-2007022494-A2 | MULTI-DRUG LIGAND CONJUGATES | ENDOCYTE, INC. (US) | 2007-02-22 | — | — | WO | claimed |
| EP-1592457-A2 | VITAMIN RECEPTOR BINDING DRUG DELIVERY CONJUGATES | Endocyte, Inc. (US) | 2005-11-09 | — | — | EP | claimed |
| US-20050002942-A1 | Minimized toxicity; eliminating pathogenic cell populations; synthesis; claimed intermediates | ENDOCYTE, INC. | 2005-01-06 | — | — | US | claimed |
| WO-2004069159-A2 | VITAMIN RECEPTOR BINDING DRUG DELIVERY CONJUGATES | ENDOCYTE, INC. (US) | 2004-08-19 | — | — | WO | claimed |
| EP-4337663-A2 | SMALL MOLECULE-BASED BI-SPECIFIC IMMUNE CELL TETHERS AND THEIR USE IN THE TREATMENT OF ENVELOPED VIRUS INFECTION | Purdue Research Foundation (US) | 2024-03-20 | — | — | EP | disclosed |
| US-20240058478-A1 | FOLATE RECEPTOR-TARGETED CONJUGATES, COMPOSITIONS, AND DELIVERY TO THE CENTRAL NERVOUS SYSTEM | PURDUE RESEARCH FOUNDATION | 2024-02-22 | — | — | US | disclosed |
| US-20240002408-A1 | FIBROBLAST ACTIVATION PROTEIN (FAP) - TARGETED ANTIFIBROTIC THERAPY | PURDUE RESEARCH FOUNDATION | 2024-01-04 | — | — | US | disclosed |
| US-20230390422-A1 | OLIGONUCLEOTIDE-BASED THERAPEUTICS AND USES THEREOF | SPEER TOD (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4274595-A1 | FOLATE RECEPTOR-TARGETED CONJUGATES, COMPOSITIONS, AND DELIVERY TO THE CENTRAL NERVOUS SYSTEM | Purdue Research Foundation (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20230346752-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION | 2023-11-02 | — | — | US | disclosed |
| WO-2009002993-A1 | CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS | ENDOCYTE, INC. (US) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008112873-A2 | BINDING LIGAND LINKED DRUG DELIVERY CONJUGATES OF TUBULYSINS | ENDOCYTE, INC. (US) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008101231-A2 | METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING KIDNEY DISEASE | ENDOCYTE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |
| EP-1592457-A2 | VITAMIN RECEPTOR BINDING DRUG DELIVERY CONJUGATES | Endocyte, Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20050002942-A1 | Minimized toxicity; eliminating pathogenic cell populations; synthesis; claimed intermediates | ENDOCYTE, INC. | 2005-01-06 | — | — | US | disclosed |
| WO-2004069159-A2 | VITAMIN RECEPTOR BINDING DRUG DELIVERY CONJUGATES | ENDOCYTE, INC. (US) | 2004-08-19 | — | — | WO | disclosed |