Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676635 | 0.72 | CYP3A4 (0.32) | CYP3A4BLM | |
| SCHEMBL4237665 | 0.72 | NOS1 (0.38) | — | |
| SCHEMBL676634 | 0.66 | KDM4E (0.43) | CYP3A4BLM | |
| SCHEMBL3454166 | 0.63 | PNP (0.32) | CYP3A4BLM | |
| SCHEMBL18686362 | 0.61 | — | — | |
| SCHEMBL2273420 | 0.60 | — | — | |
| SCHEMBL3454198 | 0.59 | CYP3A4 (0.36) | CYP3A4BLM | |
| SCHEMBL184925 | 0.58 | — | — | |
| SCHEMBL24149523 | 0.57 | CYP1A2 (0.33) | CYP3A4BLM | |
| SCHEMBL9054708 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664317-B1 | Use of precursor Z for the production of a means for therapy of human molybdenum cofactor deficiency | ALEXION PHARMA INTERNAT SARL (CH) | 2013-03-06 | — | — | EP | disclosed |
| US-7504095-B2 | 2,10-dioxo,2,12,12-trihydroxy,8-amino-4,4a,5a,6,9,10,11,11a,12,12a-decahydropterino(6',7':5,6)pyrano(2,3-d)-1,3,2-dioxaphosphorin | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2009-03-17 | — | — | US | disclosed |
| US-20070037250-A1 | 2,10-dioxo,2,12,12-trihydroxy,8-amino-4,4a,5a,6,9,10,11,11a,12,12a-decahydropterino(6',7':5,6)pyrano(2,3-d)-1,3,2-dioxaphosphorin | PHOENIX TISSUE REPAIR, INC. | 2007-02-15 | — | — | US | disclosed |
| EP-1664317-A2 | METHOD FOR OBTAINING PRECURSOR Z AND USE THEREOF FOR THE PRODUCTION OF A MEANS FOR THERAPY OF HUMAN MOLYBDENUM COFACTOR DEFICIENCY | Schwarz, Guenter (DE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005073387-A2 | METHOD FOR OBTAINING PRECURSOR Z AND USE THEREOF FOR THE PRODUCTION OF A MEANS FOR THERAPY OF HUMAN MOLYBDENUM COFACTOR DEFICIENCY | SCHWARZ GUENTER (DE) | 2005-08-11 | — | — | WO | disclosed |