SCHEMBL4237682

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4543713	0.84	TLR7 (0.58)	TLR7
	SCHEMBL4551058	0.81	ALDH1A1 (0.41)	LRRK2
	SCHEMBL4250138	0.79	TLR7 (0.35)	TLR7PDE2APDE10APIK3CAMTOR
	SCHEMBL4242862	0.79	GPR119 (0.42)	—
	SCHEMBL4250139	0.79	TLR7 (0.35)	TLR7PDE2APDE10ALRRK2BRD4
	SCHEMBL1486756	0.77	NMT1 (0.44)	—
	SCHEMBL1486683	0.77	TLR8 (0.36)	TLR7PIK3CDPIK3CAMTORLRRK2
	SCHEMBL5803504	0.75	F10 (0.37)	—
	SCHEMBL1486674	0.74	TLR7 (0.49)	TLR7PIK3CDPIK3CAMTORBRD4
	SCHEMBL4239098	0.74	TLR7 (0.41)	TLR7PDE2APDE10APDE1APDE1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.