SCHEMBL4238183

SCHEMBL4238183

O=S(=O)(O)c1cc(C=Cc2ccccc2)ccc1-c1ccc(C=Cc2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.45
MAOB P27338 2/20 0.45
PTPN1 P18031 2/20 0.44
PTPN6 P29350 1/20 0.44
PELI1 Q96FA3 1/20 0.43
SRD5A1 P18405 1/20 0.42
SRD5A2 P31213 1/20 0.42
HNF4A P41235 1/20 0.41
RELA Q04206 1/20 0.41
PDK2 Q15119 1/20 0.39
TRPV1 Q8NER1 2/20 0.39
TTR P02766 2/20 0.39
CA1 P00915 1/20 0.39
MGLL Q99685 1/20 0.39
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1170845 0.98 MAOA (0.44) MAOAMAOBPTPN1PTPN6PELI1
SCHEMBL27797862 0.92 MAOA (0.49) MAOAMAOBPTPN1PTPN6SRD5A1
SCHEMBL7590543 0.92 MAOA (0.49) MAOAMAOBPTPN1PTPN6SRD5A1
SCHEMBL11444848 0.90 MAOA (0.47) MAOAMAOBPTPN1PTPN6SRD5A1
SCHEMBL28532673 0.90 MAOA (0.47) MAOAMAOBPTPN1PTPN6SRD5A1
SCHEMBL8773475 0.83 MAOA (0.42) MAOAMAOBPTPN1PELI1SRD5A1
SCHEMBL1170842 0.83 MAOA (0.44) MAOAMAOBPTPN1PTPN6PELI1
SCHEMBL1170844 0.83 MAOA (0.44) MAOAMAOBPTPN1PTPN6PELI1
(Z)-1,2-Diphenylethene SCHEMBL27449534 0.81 PTPN1 (0.47) PTPN1PTPN6PELI1TRPV1TTR
SCHEMBL11366642 0.80 HTR2A (0.47) MAOAMAOBPTPN1HNF4ARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9839591-B2 Anionic dye or brightener bearing an ammonium or phosphonium counterion, dye composition comprising them and process for dyeing keratin fibres using these dyes L'OREAL (FR) 2017-12-12 US disclosed
US-20150113742-A1 ANIONIC DYE OR BRIGHTENER BEARING AN AMMONIUM OR PHOSPHONIUM COUNTERION, DYE COMPOSITION COMPRISING THEM AND PROCESS FOR DYEING KERATIN FIBRES USING THESE DYES L'OREAL (FR) 2015-04-30 US disclosed
EP-2854749-A2 ANIONIC DYE OR BRIGHTENER BEARING AN AMMONIUM OR PHOSPHONIUM COUNTERION, DYE COMPOSITION COMPRISING THEM AND PROCESS FOR DYEING KERATIN FIBRES USING THESE DYES L'Oréal (FR) 2015-04-08 EP disclosed
WO-2013175002-A2 ANIONIC DYE OR BRIGHTENER BEARING AN AMMONIUM OR PHOSPHONIUM COUNTERION, DYE COMPOSITION COMPRISING THEM AND PROCESS FOR DYEING KERATIN FIBRES USING THESE DYES L'OREAL (FR) 2013-11-28 WO disclosed
US-20130052247-A1 FLEXIBLE ARTICLE FOR NAILS WITH AN IMPROVED ADHESIVE LAYER L'OREAL (FR) 2013-02-28 US disclosed
US-20090126316-A1 NAIL POLISH FILM WITH OPTICAL EFFECT L'OREAL (FR) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150113742-A1 ANIONIC DYE OR BRIGHTENER BEARING AN AMMONIUM OR PHOSPHONIUM COUNTERION, DYE COMPOSITION COMPRISING THEM AND PROCESS FOR DYEING KERATIN FIBRES USING THESE DYES KRT18, IK, COL14A1 MAOA 3353/4885MAOB 3220/4885PTPN1 3237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.