Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4238183 | 0.98 | MAOA (0.45) | MAOAMAOBPTPN1PTPN6PELI1 | |
| SCHEMBL11444848 | 0.92 | MAOA (0.47) | MAOAMAOBPTPN1PTPN6SRD5A1 | |
| SCHEMBL28532673 | 0.92 | MAOA (0.47) | MAOAMAOBPTPN1PTPN6SRD5A1 | |
| SCHEMBL27797862 | 0.90 | MAOA (0.49) | MAOAMAOBPTPN1PTPN6SRD5A1 | |
| SCHEMBL7590543 | 0.90 | MAOA (0.49) | MAOAMAOBPTPN1PTPN6SRD5A1 | |
| SCHEMBL8773475 | 0.82 | MAOA (0.42) | MAOAMAOBPTPN1PELI1SRD5A1 | |
| SCHEMBL1170842 | 0.81 | MAOA (0.44) | MAOAMAOBPTPN1PTPN6PELI1 | |
| SCHEMBL1170844 | 0.81 | MAOA (0.44) | MAOAMAOBPTPN1PTPN6PELI1 | |
| (Z)-1,2-Diphenylethene SCHEMBL27449534 | 0.80 | PTPN1 (0.47) | PTPN1PTPN6PELI1TRPV1TTR | |
| SCHEMBL11366643 | 0.79 | HTR2A (0.47) | MAOAMAOBPTPN1HNF4ARELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555009-B1 | Skin make-up composition | OREAL (FR) | 2010-07-14 | — | — | EP | claimed |
| US-7261744-B2 | Method for dyeing or coloring human keratin materials with lightening effect using a composition comprising at least one fluorescent compound and at least one optical brightener | L'OREAL S.A. (FR) | 2007-08-28 | — | — | US | claimed |
| US-20060010617-A1 | Method for dyeing or coloring human keratin materials with lightening effect using a composition comprising at least one fluorescent compound and at least one optical brightener | L'OREAL S.A. (FR) | 2006-01-19 | — | — | US | claimed |
| US-20050175562-A1 | crosslinked organopolysiloxane having dimethylvinylsiloxy end groups and a methylhydropolysiloxane having trimethylsiloxy end groups; water, oil, water soluble sovlent as liquid binder; and goniochromatic / photochromic or fluorescent coloring agents; cosmetic | L'OREAL S.A. (FR) | 2005-08-11 | — | — | US | claimed |
| US-20050031559-A1 | Mineral particles containing optical brightener for lightening the face skin; mixture of silica, hydroxyapatite particles and dyes of stilbene, or coumarin; foundation powders with concealing properties | L'OREAL (FR) | 2005-02-10 | — | — | US | claimed |
| EP-4593792-A1 | COSMETIC HAIR CARE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR AMINO SILICONE AND AT LEAST ONE COLOURING AGENT AND/OR AN OPTICAL BRIGHTENER, AND COSMETIC HAIR TREATMENT PROCESS | L'OREAL (FR) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024068929-A1 | COSMETIC HAIR CARE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR AMINO SILICONE AND AT LEAST ONE COLOURING AGENT AND/OR AN OPTICAL BRIGHTENER, AND COSMETIC HAIR TREATMENT PROCESS | L'OREAL (FR) | 2024-04-04 | — | — | WO | disclosed |
| US-10173080-B2 | Dehydroascorbic acid or monomeric, polymeric or isomeric derivative thereof and an amine for artificially coloring the skin | L'OREAL (FR) | 2019-01-08 | — | — | US | disclosed |
| US-20180140519-A1 | ASSEMBLY AND PROCESS FOR MAKING UP A KERATIN MATERIAL | L'OREAL (FR) | 2018-05-24 | — | — | US | disclosed |
| US-9956147-B2 | Emulsion containing a dispersion of bismuth oxychloride | L'OREAL (FR) | 2018-05-01 | — | — | US | disclosed |
| US-9643032-B2 | Application of dehydroascorbic acid or derivatives/isomers thereof for artificially coloring the skin | L'OREAL (FR) | 2017-05-09 | — | — | US | disclosed |
| EP-3157635-A1 | ASSEMBLY AND PROCESS FOR MAKING UP A KERATIN MATERIAL | L'OREAL (FR) | 2017-04-26 | — | — | EP | disclosed |
| US-20090016974-A1 | Application of dehydroascorbic acid or derivatives/isomers thereof for artificially coloring the skin | L'OREAL (FR) | 2009-01-15 | — | — | US | disclosed |
| US-7261744-B2 | Method for dyeing or coloring human keratin materials with lightening effect using a composition comprising at least one fluorescent compound and at least one optical brightener | L'OREAL S.A. (FR) | 2007-08-28 | — | — | US | disclosed |
| WO-2007042945-A2 | PROCESS FOR MAKING UP OR CARING FOR THE NAILS WITH CYANOACRYLATE MONOMER | L'OREAL (FR) | 2007-04-19 | — | — | WO | disclosed |
| US-20070059269-A1 | Administration of 8-hexadecene-1,16-dicarboxylic acid for promoting cohesion of the epidermal horny layer | L'OREAL (FR) | 2007-03-15 | — | — | US | disclosed |
| US-20060010617-A1 | Method for dyeing or coloring human keratin materials with lightening effect using a composition comprising at least one fluorescent compound and at least one optical brightener | L'OREAL S.A. (FR) | 2006-01-19 | — | — | US | disclosed |
| US-20050175562-A1 | crosslinked organopolysiloxane having dimethylvinylsiloxy end groups and a methylhydropolysiloxane having trimethylsiloxy end groups; water, oil, water soluble sovlent as liquid binder; and goniochromatic / photochromic or fluorescent coloring agents; cosmetic | L'OREAL S.A. (FR) | 2005-08-11 | — | — | US | disclosed |
| US-20050031559-A1 | Mineral particles containing optical brightener for lightening the face skin; mixture of silica, hydroxyapatite particles and dyes of stilbene, or coumarin; foundation powders with concealing properties | L'OREAL (FR) | 2005-02-10 | — | — | US | disclosed |
| US-20040241115-A1 | Nail varnish composition comprising fibers covered with at least one fluorescent whitening agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090016974-A1 | Application of dehydroascorbic acid or derivatives/isomers thereof for artificially coloring the skin | ADH7, ADH1B, TYR | MAOA 162/4885MAOB 150/4885PTPN1 2162/4885 |
| US-20070059269-A1 | Administration of 8-hexadecene-1,16-dicarboxylic acid for promoting cohesion of the epidermal horny layer | DSG1, CUTA, DSC1 | MAOA 3332/4885MAOB 4153/4885PTPN1 4803/4885 |
| US-20040241115-A1 | Nail varnish composition comprising fibers covered with at least one fluorescent whitening agent | POLR1C, NACA, DPM1 | MAOA 193/4885MAOB 652/4885PTPN1 192/4885 |
| US-10173080-B2 | Dehydroascorbic acid or monomeric, polymeric or isomeric derivative thereof and an amine for artificially coloring the skin | OXER1, AKR1B10, RBP1 | MAOA 759/4885MAOB 508/4885PTPN1 3083/4885 |
| US-20060010617-A1 | Method for dyeing or coloring human keratin materials with lightening effect using a composition comprising at least one fluorescent compound and at least one optical brightener | KRT18, IK, CUTA | MAOA 501/4885MAOB 1471/4885PTPN1 4822/4885 |
| US-20050175562-A1 | crosslinked organopolysiloxane having dimethylvinylsiloxy end groups and a methylhydropolysiloxane having trimethylsiloxy end groups; water, oil, water soluble sovlent as liquid binder; and goniochromatic / photochromic or fluorescent coloring agents; cosmetic | MICA, MITF, CUTA | MAOA 3648/4885MAOB 3669/4885PTPN1 3121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.