Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 known ✓ | Q15119 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170842 | 1.00 | MAOA (0.44) | MAOAMAOBPTPN1PTPN6RELA | |
| SCHEMBL11444847 | 0.92 | MAOA (0.47) | MAOAMAOBPTPN1RELACYP1A1 | |
| SCHEMBL1943906 | 0.92 | MAOA (0.47) | MAOAMAOBPTPN1RELACYP1A1 | |
| SCHEMBL4238183 | 0.83 | MAOA (0.45) | MAOAMAOBPTPN1PTPN6RELA | |
| (Z)-1,2-Diphenylethene SCHEMBL29093047 | 0.82 | PTPN1 (0.43) | MAOBPTPN1PTPN6PELI1TRPV1 | |
| SCHEMBL1170845 | 0.81 | MAOA (0.44) | MAOAMAOBPTPN1PTPN6RELA | |
| SCHEMBL30835513 | 0.78 | PTPN1 (0.40) | MAOAMAOBPTPN1PTPN6PELI1 | |
| SCHEMBL6330115 | 0.78 | PTGS2 (0.35) | MAOAMAOBPTPN1PTPN6TRPV1 | |
| Sulfuric Acid SCHEMBL20893319 | 0.77 | NFE2L2 (0.46) | MAOAMAOBRELANFE2L2CYP19A1 | |
| SCHEMBL15534781 | 0.77 | RAD51 (0.45) | PTPN1RELACYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555009-B1 | Skin make-up composition | OREAL (FR) | 2010-07-14 | — | — | EP | claimed |
| US-20080184495-A1 | Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition | L'OREAL S.A. (FR) | 2008-08-07 | — | — | US | claimed |
| US-7261744-B2 | Method for dyeing or coloring human keratin materials with lightening effect using a composition comprising at least one fluorescent compound and at least one optical brightener | L'OREAL S.A. (FR) | 2007-08-28 | — | — | US | claimed |
| US-20060010617-A1 | Method for dyeing or coloring human keratin materials with lightening effect using a composition comprising at least one fluorescent compound and at least one optical brightener | L'OREAL S.A. (FR) | 2006-01-19 | — | — | US | claimed |
| US-20050175562-A1 | crosslinked organopolysiloxane having dimethylvinylsiloxy end groups and a methylhydropolysiloxane having trimethylsiloxy end groups; water, oil, water soluble sovlent as liquid binder; and goniochromatic / photochromic or fluorescent coloring agents; cosmetic | L'OREAL S.A. (FR) | 2005-08-11 | — | — | US | claimed |
| US-20050031559-A1 | Mineral particles containing optical brightener for lightening the face skin; mixture of silica, hydroxyapatite particles and dyes of stilbene, or coumarin; foundation powders with concealing properties | L'OREAL (FR) | 2005-02-10 | — | — | US | claimed |
| EP-4593792-A1 | COSMETIC HAIR CARE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR AMINO SILICONE AND AT LEAST ONE COLOURING AGENT AND/OR AN OPTICAL BRIGHTENER, AND COSMETIC HAIR TREATMENT PROCESS | L'OREAL (FR) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024068929-A1 | COSMETIC HAIR CARE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR AMINO SILICONE AND AT LEAST ONE COLOURING AGENT AND/OR AN OPTICAL BRIGHTENER, AND COSMETIC HAIR TREATMENT PROCESS | L'OREAL (FR) | 2024-04-04 | — | — | WO | disclosed |
| US-10173080-B2 | Dehydroascorbic acid or monomeric, polymeric or isomeric derivative thereof and an amine for artificially coloring the skin | L'OREAL (FR) | 2019-01-08 | — | — | US | disclosed |
| US-20180140519-A1 | ASSEMBLY AND PROCESS FOR MAKING UP A KERATIN MATERIAL | L'OREAL (FR) | 2018-05-24 | — | — | US | disclosed |
| US-9956147-B2 | Emulsion containing a dispersion of bismuth oxychloride | L'OREAL (FR) | 2018-05-01 | — | — | US | disclosed |
| US-9643032-B2 | Application of dehydroascorbic acid or derivatives/isomers thereof for artificially coloring the skin | L'OREAL (FR) | 2017-05-09 | — | — | US | disclosed |
| EP-3157635-A1 | ASSEMBLY AND PROCESS FOR MAKING UP A KERATIN MATERIAL | L'OREAL (FR) | 2017-04-26 | — | — | EP | disclosed |
| WO-2007042945-A2 | PROCESS FOR MAKING UP OR CARING FOR THE NAILS WITH CYANOACRYLATE MONOMER | L'OREAL (FR) | 2007-04-19 | — | — | WO | disclosed |
| US-20070059269-A1 | Administration of 8-hexadecene-1,16-dicarboxylic acid for promoting cohesion of the epidermal horny layer | L'OREAL (FR) | 2007-03-15 | — | — | US | disclosed |
| US-20060010617-A1 | Method for dyeing or coloring human keratin materials with lightening effect using a composition comprising at least one fluorescent compound and at least one optical brightener | L'OREAL S.A. (FR) | 2006-01-19 | — | — | US | disclosed |
| US-20050175562-A1 | crosslinked organopolysiloxane having dimethylvinylsiloxy end groups and a methylhydropolysiloxane having trimethylsiloxy end groups; water, oil, water soluble sovlent as liquid binder; and goniochromatic / photochromic or fluorescent coloring agents; cosmetic | L'OREAL S.A. (FR) | 2005-08-11 | — | — | US | disclosed |
| US-20050048023-A1 | Composition comprising at least one conductive polymer and at least one fluorescent dye and/or at least one optical brightener, and process for use thereof | L'OREAL S.A. (FR) | 2005-03-03 | — | — | US | disclosed |
| US-20050031559-A1 | Mineral particles containing optical brightener for lightening the face skin; mixture of silica, hydroxyapatite particles and dyes of stilbene, or coumarin; foundation powders with concealing properties | L'OREAL (FR) | 2005-02-10 | — | — | US | disclosed |
| US-20040241115-A1 | Nail varnish composition comprising fibers covered with at least one fluorescent whitening agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080184495-A1 | Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition | KRT18, VIM, CD44 | PDK2 1356/4885MAOA 736/4885MAOB 997/4885 |
| US-20070059269-A1 | Administration of 8-hexadecene-1,16-dicarboxylic acid for promoting cohesion of the epidermal horny layer | DSG1, CUTA, DSC1 | PDK2 316/4885MAOA 3332/4885MAOB 4153/4885 |
| US-20040241115-A1 | Nail varnish composition comprising fibers covered with at least one fluorescent whitening agent | POLR1C, NACA, DPM1 | PDK2 4740/4885MAOA 193/4885MAOB 652/4885 |
| US-10173080-B2 | Dehydroascorbic acid or monomeric, polymeric or isomeric derivative thereof and an amine for artificially coloring the skin | OXER1, AKR1B10, RBP1 | PDK2 262/4885MAOA 759/4885MAOB 508/4885 |
| US-20060010617-A1 | Method for dyeing or coloring human keratin materials with lightening effect using a composition comprising at least one fluorescent compound and at least one optical brightener | KRT18, IK, CUTA | PDK2 460/4885MAOA 501/4885MAOB 1471/4885 |
| US-20050048023-A1 | Composition comprising at least one conductive polymer and at least one fluorescent dye and/or at least one optical brightener, and process for use thereof | KRT18, DSG1, DSP | PDK2 1849/4885MAOA 1984/4885MAOB 3499/4885 |
| US-20050175562-A1 | crosslinked organopolysiloxane having dimethylvinylsiloxy end groups and a methylhydropolysiloxane having trimethylsiloxy end groups; water, oil, water soluble sovlent as liquid binder; and goniochromatic / photochromic or fluorescent coloring agents; cosmetic | MICA, MITF, CUTA | PDK2 4342/4885MAOA 3648/4885MAOB 3669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.