SCHEMBL4238588

SCHEMBL4238588

CCCCCCCC/C=C\CCCCCCCC(=O)NC(C)CO

nearest known ligand 0.91

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.83
THRB P10828 2/20 0.83
KCNK3 O14649 1/20 0.83
ALDH1A1 P00352 1/20 0.83
BLM P54132 1/20 0.83
TDP1 Q9NUW8 1/20 0.83
LPAR3 Q9UBY5 1/20 0.65
DEGS1 O15121 1/20 0.64
CETP P11597 2/20 0.63
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
ASAH2 Q9NR71 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7617846 1.00 CNR2 (0.83) CNR2THRBKCNK3ALDH1A1BLM
SCHEMBL7620441 1.00 CNR2 (0.83) CNR2THRBKCNK3ALDH1A1BLM
SCHEMBL7622699 1.00 CNR2 (0.83) CNR2THRBKCNK3ALDH1A1BLM
SCHEMBL7617717 1.00 CNR2 (0.83) CNR2THRBKCNK3ALDH1A1BLM
SCHEMBL7623460 1.00 CNR2 (0.83) CNR2THRBKCNK3ALDH1A1BLM
SCHEMBL4327695 1.00 CNR2 (0.83) CNR2THRBKCNK3ALDH1A1BLM
SCHEMBL4320015 1.00 CNR2 (0.83) CNR2THRBKCNK3ALDH1A1BLM
SCHEMBL16909345 1.00 CNR2 (0.83) CNR2THRBKCNK3ALDH1A1BLM
SCHEMBL7620523 1.00 CNR2 (0.83) CNR2THRBKCNK3ALDH1A1BLM
SCHEMBL7620584 1.00 CNR2 (0.83) CNR2THRBKCNK3ALDH1A1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101247797-A Inhibitors of anorexic lipid hydrolysis for the treatment of eating disorders RHEOSCIENCE AS (DK) 2008-08-20 CN claimed
US-20090054526-A1 INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS UNIVERSITY OF COPENHAGEN (DK) 2009-02-26 US disclosed
CN-101247797-A Inhibitors of anorexic lipid hydrolysis for the treatment of eating disorders RHEOSCIENCE AS (DK) 2008-08-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054526-A1 INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS LIPE, PNLIP, FAAH2 CNR2 460/4885THRB 217/4885KCNK3 3317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.