Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | GFER | P55789 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | MPO | P05164 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PTGES | O14684 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | TYMP | P19971 | 1/20 | 0.54 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034107 | 0.83 | MEN1 (0.70) | MEN1KMT2AGFERRAB9AMPO | |
| SCHEMBL4241019 | 0.81 | MEN1 (0.67) | MEN1KMT2AGFERRAB9AMPO | |
| SCHEMBL4242132 | 0.81 | MEN1 (0.67) | MEN1KMT2AGFERRAB9AMPO | |
| SCHEMBL4241931 | 0.79 | MEN1 (0.65) | MEN1KMT2AGFERRAB9AMPO | |
| SCHEMBL8770855 | 0.79 | NPC1 (0.74) | MEN1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL4246473 | 0.78 | MEN1 (0.64) | MEN1KMT2AGFERRAB9AMPO | |
| SCHEMBL13984125 | 0.76 | ALDH1A1 (0.92) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL5567676 | 0.76 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL18085798 | 0.74 | PTPN1 (1.00) | MEN1KMT2ARAB9AKDM4EPTPN1 | |
| SCHEMBL4238485 | 0.73 | PTPN1 (0.59) | MEN1KMT2AGFERRAB9AMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105217-A1 | 2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105217-A1 | 2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | CHRNA7, CHRNA5, CHRNA2 | MEN1 4763/4885KMT2A 2842/4885GFER 2730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.