Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | C1S | P09871 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1034550 | 0.98 | BLM (0.46) | F2F10F12F7F3 | |
| SCHEMBL7863179 | 0.82 | ALDH1A1 (0.41) | F2F10F12F7F3 | |
| SCHEMBL8887730 | 0.82 | TSHR (0.53) | MIFKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL10495281 | 0.81 | F2 (0.55) | F2F10F12F7F3 | |
| SCHEMBL6957591 | 0.79 | ALDH1A1 (0.40) | L3MBTL1NPC1RAB9AMIFKMT2A | |
| Hydrochloric Acid SCHEMBL29008442 | 0.78 | BLM (0.57) | F2F10F12F7F3 | |
| Hydrochloric Acid SCHEMBL28555632 | 0.78 | BLM (0.57) | F2F10F12F7F3 | |
| SCHEMBL4509521 | 0.78 | C1S (0.39) | F2F10F12F7F3 | |
| SCHEMBL23978028 | 0.75 | NPC1 (0.41) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2554580 | 0.75 | L3MBTL1 (0.48) | L3MBTL1NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084110-A | 3- amino benzo [d] isothiazole, derivative and its synthetic method | 湘潭大学 | 2018-05-29 | — | — | CN | claimed |
| EP-0103126-B1 | PROCESS FOR PREPARING 4-AMINO-5-DIALKOXYMETHYLPYRIMIDINE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1987-03-04 | — | — | EP | claimed |
| US-4492792-A | Process for preparing 4-amino-5-dialkoxy-methylpyrimidine derivatives | UBE INDUSTRIES, LTD. (JP) | 1985-01-08 | — | — | US | claimed |
| EP-0103126-A1 | Process for preparing 4-amino-5-dialkoxymethylpyrimidine derivatives | UBE INDUSTRIES, LTD. (JP) | 1984-03-21 | — | — | EP | claimed |
| US-11737349-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
| US-11737349-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
| CN-108084110-B | 3-aminobenzo [ d ] isothiazole, derivative and synthetic method thereof | 湘潭大学 | 2021-05-07 | — | — | CN | disclosed |
| EP-3750897-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2020-12-16 | — | — | EP | disclosed |
| CN-109468659-A | The method of room temperature synthesizing benzimidazole under the conditions of electrocatalytic method water phase | 云南师范大学 | 2019-03-15 | — | — | CN | disclosed |
| CN-109456273-A | The method of benzenecarboximidamide class compound synthesis benzimidazole compound is used in microwave method water phase | 云南师范大学 | 2019-03-12 | — | — | CN | disclosed |
| CN-108997194-A | A kind of synthetic method of amino isoindole derivatives | 温州大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-108084110-A | 3- amino benzo [d] isothiazole, derivative and its synthetic method | 湘潭大学 | 2018-05-29 | — | — | CN | disclosed |
| WO-2011151434-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |
| US-20090131424-A1 | THIAZOLYL-DIHYDRO-CHINAZOLINE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-21 | — | — | US | disclosed |
| EP-2007772-A1 | THIAZOLYL-DIHYDROQUINAZOLINES | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007115932-A1 | THIAZOLYL-DIHYDROQUINAZOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |
| US-20070238746-A1 | THIAZOLYL-DIHYDRO-CHINAZOLINE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
| EP-0103126-B1 | PROCESS FOR PREPARING 4-AMINO-5-DIALKOXYMETHYLPYRIMIDINE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1987-03-04 | — | — | EP | disclosed |
| US-4492792-A | Process for preparing 4-amino-5-dialkoxy-methylpyrimidine derivatives | UBE INDUSTRIES, LTD. (JP) | 1985-01-08 | — | — | US | disclosed |
| EP-0103126-A1 | Process for preparing 4-amino-5-dialkoxymethylpyrimidine derivatives | UBE INDUSTRIES, LTD. (JP) | 1984-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11737349-B2 | Organic electroluminescent materials and devices | OCIAD2, OCIAD1, OTC | F2 2272/4885F10 3040/4885F12 4526/4885 |
| US-20070238746-A1 | THIAZOLYL-DIHYDRO-CHINAZOLINE | CYP3A7, UGT2B7, UGT1A7 | F2 2981/4885F10 4094/4885F12 1219/4885 |
| US-20090131424-A1 | THIAZOLYL-DIHYDRO-CHINAZOLINE | CYP3A7, UGT2B7, UGT1A7 | F2 2981/4885F10 4094/4885F12 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.