Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235797 | 0.72 | KDR (0.40) | MEN1KMT2ANPC1RAB9ACASP3 | |
| SCHEMBL4243041 | 0.70 | SCD (0.43) | ADORA3CDK5CDK5R1 | |
| SCHEMBL4239760 | 0.69 | MET (0.38) | MEN1KMT2ANPC1RAB9ACASP3 | |
| SCHEMBL3359286 | 0.69 | NPC1 (0.46) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL4241649 | 0.68 | GRK2 (0.40) | MEN1KMT2ANPC1RAB9ACASP3 | |
| SCHEMBL4243223 | 0.68 | NPC1 (0.42) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL4236523 | 0.68 | EGFR (0.41) | MEN1KMT2ANPC1RAB9APIK3CD | |
| Hydrochloric Acid SCHEMBL4234156 | 0.67 | EGFR (0.41) | MEN1KMT2ANPC1RAB9APIK3CD | |
| SCHEMBL12989108 | 0.67 | ALDH1A1 (0.42) | MEN1KMT2ARAB9AMAPTHTT | |
| SCHEMBL3911186 | 0.67 | ABCG2 (0.56) | MEN1KMT2ANPC1RAB9APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010871-A2 | PYRAZOLE DERIVATIVES AS ANTAGONISTS OF ADENOSINE A3 RECEPTOR | ADDEX PHARMA S.A. (CH) | 2009-01-22 | — | — | WO | disclosed |