Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 13/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235797 | 0.81 | KDR (0.40) | — | |
| SCHEMBL4239760 | 0.79 | MET (0.38) | — | |
| SCHEMBL4233124 | 0.77 | NPC1 (0.36) | — | |
| SCHEMBL4236523 | 0.77 | EGFR (0.41) | ADORA2BADORA3ADORA1ADORA2A | |
| Hydrochloric Acid SCHEMBL4234156 | 0.77 | EGFR (0.41) | ADORA2BADORA3ADORA1ADORA2A | |
| SCHEMBL4243830 | 0.76 | EGFR (0.39) | ADORA3ADORA2ACDK5 | |
| SCHEMBL4241653 | 0.74 | JAK2 (0.40) | SCDCDK5 | |
| SCHEMBL4241649 | 0.70 | GRK2 (0.40) | ADORA3CDK5 | |
| SCHEMBL4239119 | 0.70 | MEN1 (0.42) | ADORA3CDK5CDK5R1 | |
| SCHEMBL3359286 | 0.69 | NPC1 (0.46) | ADORA3CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010871-A2 | PYRAZOLE DERIVATIVES AS ANTAGONISTS OF ADENOSINE A3 RECEPTOR | ADDEX PHARMA S.A. (CH) | 2009-01-22 | — | — | WO | claimed |