Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | DAO | P14920 | 7/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SOD1 | P00441 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22624852 | 0.72 | ABL1 (0.39) | MAPK13MAPK12MAPK11MAPK14CRBN | |
| SCHEMBL12297819 | 0.71 | SOD1 (0.70) | MAOAMAOBDAOSOD1 | |
| SCHEMBL4243774 | 0.71 | NSD2 (0.54) | MAOAMAOBDAO | |
| SCHEMBL12040303 | 0.70 | MAOA (0.54) | MAOAMAOBDAOPKM | |
| SCHEMBL24416393 | 0.69 | ABL1 (0.37) | DAO | |
| SCHEMBL21961226 | 0.68 | ABL1 (0.36) | — | |
| SCHEMBL3595568 | 0.68 | ALDH1A1 (0.51) | MAOAMAOBDAOSOD1 | |
| SCHEMBL1724299 | 0.68 | MAOA (0.56) | MAOAMAOBDAOSOD1 | |
| SCHEMBL1104966 | 0.67 | MAOA (0.59) | MAOAMAOBHTT | |
| SCHEMBL6929568 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120655-A1 | INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | WO | disclosed |