Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4239309 | 0.75 | HTT (0.37) | POLBKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11821422 | 0.75 | CYP1A2 (0.48) | POLBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8021561 | 0.71 | ALDH1A1 (0.39) | POLBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL11920949 | 0.70 | ALDH1A1 (0.39) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL11093234 | 0.70 | ALDH1A1 (0.39) | CYP11B1CYP11B2KDM4EALDH1A1LMNA | |
| SCHEMBL734030 | 0.69 | KCNN4 (0.42) | POLBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL3932718 | 0.67 | ALDH1A1 (0.41) | LTA4HCYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL10249534 | 0.67 | RAB9A (0.42) | KDM4ESMN1; SMN2 | |
| SCHEMBL4431139 | 0.67 | CNR1 (0.41) | POLBALDH1A1LMNAMAPTHPGD | |
| SCHEMBL19145997 | 0.66 | ALDH1A1 (0.42) | POLBKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |