Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4239306 | 0.75 | POLB (0.34) | ALDH1A1KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL11821422 | 0.73 | CYP1A2 (0.48) | HTTALDH1A1KDM4ETDP1POLB | |
| SCHEMBL29015481 | 0.73 | HTR6 (0.46) | ALDH1A1KDM4ELMNAHTR2CKDM1A | |
| SCHEMBL13309267 | 0.72 | NPC1 (0.48) | ALDH1A1HTR2CTDP1KDM1AMAOA | |
| SCHEMBL4239275 | 0.72 | TACR3 (0.41) | ALDH1A1HTR2CTDP1KDM1AMAOA | |
| SCHEMBL3375069 | 0.71 | TDP1 (0.47) | ALDH1A1LMNAHTR2CTDP1KDM1A | |
| SCHEMBL8021561 | 0.70 | ALDH1A1 (0.39) | HTTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL4231904 | 0.69 | TACR3 (0.46) | ALDH1A1LMNAHTR2CTDP1KDM1A | |
| SCHEMBL3376524 | 0.69 | KDM1A (0.37) | ALDH1A1LMNAHTR2CKDM1AMAOA | |
| SCHEMBL11093234 | 0.69 | ALDH1A1 (0.39) | HTTALDH1A1KDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |