Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11802878 | 0.85 | TSHR (0.39) | TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL28150925 | 0.84 | TSHR (0.43) | TSHRLMNATDP1 | |
| SCHEMBL28949263 | 0.83 | TSHR (0.47) | TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL14036720 | 0.81 | TSHR (0.45) | TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL4889295 | 0.79 | TSHR (0.43) | TSHRLMNATDP1 | |
| SCHEMBL20577887 | 0.79 | LMNA (0.50) | TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL13966459 | 0.78 | TSHR (0.35) | TSHRTDP1ALDH1A1 | |
| SCHEMBL7219024 | 0.78 | LMNA (0.48) | TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL4893502 | 0.77 | TSHR (0.41) | TSHRLMNA | |
| SCHEMBL4889479 | 0.77 | TSHR (0.41) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3039740-B1 | METHOD FOR PREPARATION OF CYANO COMPOUNDS OF THE 13TH GROUP WITH A LEWIS ACID | LONZA AG (CH) | 2016-11-09 | — | — | EP | disclosed |
| WO-2016162400-A1 | METHOD FOR PREPARATION OF CYANO COMPOUNDS OF BORON WITH A BRONSTEDT ACID | LONZA LTD (CH) | 2016-10-13 | — | — | WO | disclosed |
| EP-3078668-A1 | METHOD FOR PREPARATION OF FLUORO CYANO COMPOUNDS OF THE 15TH GROUP WITH A BRONSTEDT ACID | Lonza Ltd (CH) | 2016-10-12 | — | — | EP | disclosed |
| US-9458180-B2 | Method for preparation of cyano compounds of the 13th group with a lewis acid | LONZA LTD. (CH) | 2016-10-04 | — | — | US | disclosed |
| US-20160229874-A1 | Method for Preparation of Cyano Compounds of the 13th Group with a Lewis Acid | LONZA LTD. (CH) | 2016-08-11 | — | — | US | disclosed |
| EP-3039740-A1 | METHOD FOR PREPARATION OF CYANO COMPOUNDS OF THE 13TH GROUP WITH A LEWIS ACID | Lonza Ltd (CH) | 2016-07-06 | — | — | EP | disclosed |
| WO-2015067404-A1 | METHOD FOR PREPARATION OF FLUORO CYANO COMPOUNDS OF THE 15TH GROUP WITH A LEWIS ACID | LONZA LTD (CH) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015067405-A1 | METHOD FOR PREPARATION OF CYANO COMPOUNDS OF THE 13TH GROUP WITH A LEWIS ACID | LONZA LTD (CH) | 2015-05-14 | — | — | WO | disclosed |
| WO-2014167035-A1 | METHOD FOR PREPARATION OF FLUORO AND CHLORO CYANO COMPOUNDS OF THE 15TH GROUP | LONZA LTD (CH) | 2014-10-16 | — | — | WO | disclosed |
| WO-2014167034-A2 | FLUORO AND CHLORO CYANO COMPOUNDS OF THE 15TH GROUP | LONZA LTD (CH) | 2014-10-16 | — | — | WO | disclosed |
| US-4351768-A | CARBONLESS, DUPLICATION, INDOLE DYES | STERLING DRUG INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4322352-A | Indolyl phthalide compounds | STERLING DRUG INC. (US) | 1982-03-30 | — | — | US | disclosed |
| US-4307018-A | CHROMOGENS FOR COPYING SYSTEMS | STERLING DRUG INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4255577-A | Process and intermediates for preparing 3-[4-(disubstituted-amino)phenyl] or | STERLING DRUG INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4251092-A | COATED WITH A 3-HETERO-3-(DIPHENYLAMINO)PHTHALIDES COLOR FORMER | STERLING DRUG INC. (US) | 1981-02-17 | — | — | US | disclosed |
| US-4200313-A | Carbonless duplicating systems | STERLING DRUG INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4189171-A | PRESSURE SENSITIVE, THERMAL AND HECTOGRAPHIC SYSTEMS | STERLING DRUG INC. (US) | 1980-02-19 | — | — | US | disclosed |
| US-4187223-A | 3-[4-(Disubstituted-amino)phenyl]-3-(diphenylamino)phthalides | STERLING DRUG INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4182714-A | CARBONLESS COLORING DUPLICATING | STERLING DRUG INC. (US) | 1980-01-08 | — | — | US | disclosed |
| US-4168378-A | THERMOGRAPHY, LEUCO DYES | STERLING DRUG INC. (US) | 1979-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229874-A1 | Method for Preparation of Cyano Compounds of the 13th Group with a Lewis Acid | CA4, CA13, CA7 | TSHR 1134/4885LMNA 283/4885TDP1 3661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.