Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20577887 | 0.85 | LMNA (0.50) | TSHRLMNATDP1 | |
| SCHEMBL8901993 | 0.84 | LMNA (0.43) | TSHRLMNATHRB | |
| SCHEMBL14036720 | 0.82 | TSHR (0.45) | TSHRLMNATDP1 | |
| SCHEMBL28321735 | 0.82 | TDP1 (0.38) | TSHRTDP1THRB | |
| SCHEMBL9506729 | 0.81 | LMNA (0.42) | TSHRLMNATHRB | |
| SCHEMBL15800763 | 0.81 | LMNA (0.42) | TSHRLMNATHRB | |
| SCHEMBL17951325 | 0.81 | LMNA (0.42) | TSHRLMNATHRB | |
| SCHEMBL28949263 | 0.79 | TSHR (0.47) | TSHRLMNATDP1 | |
| SCHEMBL5931043 | 0.79 | — | — | |
| SCHEMBL1054310 | 0.79 | LMNA (0.37) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293880-A1 | Liquid, Thermally Curable Mixtures, Their Preparation and Use | BASF COATINGS AG (DE) | 2008-11-27 | — | — | US | claimed |