Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893502 | 0.85 | TSHR (0.41) | TSHRLMNATRPA1 | |
| SCHEMBL20577887 | 0.82 | LMNA (0.50) | TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL4889295 | 0.82 | TSHR (0.43) | TSHRLMNATDP1 | |
| SCHEMBL28949263 | 0.81 | TSHR (0.47) | TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL423939 | 0.81 | TSHR (0.47) | TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL4892813 | 0.80 | LMNA (0.38) | TSHRLMNATRPA1 | |
| SCHEMBL1660076 | 0.78 | TSHR (0.50) | TSHRTDP1ALDH1A1 | |
| SCHEMBL4890348 | 0.77 | THRB (0.39) | TSHRLMNA | |
| SCHEMBL597793 | 0.76 | — | — | |
| SCHEMBL19158064 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135208-A1 | FLUOROCARBON POLYMER-FREE PREPARATIONS BASED ON WATER AND/OR ORGANIC SOLVENTS AND THE USE THEREOF AS A FINISH ON FLEXIBLE SHEET MATERIAL | RUDOLF GMBH & CO. KG CHEMISCHE FABRIK (DE) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008000816-A1 | METHOD FOR WATERPROOFING A SUBSTRATE | BLUESTAR SILICONES FRANCE (FR) | 2008-01-03 | — | — | WO | disclosed |