⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3696016 | 0.83 | PDE4A (0.36) | — | |
| SCHEMBL3700645 | 0.79 | TNKS2 (0.43) | — | |
| SCHEMBL9298002 | 0.79 | — | — | |
| SCHEMBL5010452 | 0.79 | — | — | |
| SCHEMBL10762574 | 0.78 | ALDH1A1 (0.34) | — | |
| SCHEMBL8516248 | 0.76 | HMGCR (0.47) | — | |
| SCHEMBL9724403 | 0.75 | HSD17B10 (0.50) | — | |
| SCHEMBL10759911 | 0.75 | MAPT (0.37) | — | |
| SCHEMBL3703023 | 0.74 | HTR2A (0.32) | — | |
| SCHEMBL6793770 | 0.74 | IDO1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201826-A1 | CONJUGATED POLYMERS FROM SUBSTITUTED 3,4-PROPYLENEDIOXYTHIOPHENE, COMPOSITIONS, METHOD OF MAKING, AND USE THEREOF | SOTZING GREGORY A | 2011-08-18 | — | — | US | disclosed |
| US-7491735-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2009-02-17 | — | — | US | disclosed |
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| US-7342116-B2 | Process for producing heterocyclic aldehyde | KOEI CHEMICAL CO., LTD. (JP) | 2008-03-11 | — | — | US | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| US-20050277670-A1 | Chemokine receptor binding compounds | ANORMED INC. | 2005-12-15 | — | — | US | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |
| US-20050124807-A1 | oxidation of a hetero alcohol in presence od an 2,2,6,6-teraalkylpiperidin-1-oxy comound | KOEI CHEMICAL CO., LTD. (JP) | 2005-06-09 | — | — | US | disclosed |
| CN-1511140-A | Oxime ether compound and agricultural or horticultural bactericide | �ձ�������ʽ���� | 2004-07-07 | — | — | CN | disclosed |
| US-20040116480-A1 | Oxime ether compound and agricultural or horticultural bactericide | NIPPON SODA CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| US-6730694-B1 | SPLA2 IS A RATE LIMITING ENZYME IN THE ARACHIDONIC ACID CASCADE WHICH HYDROLYZES MEMBRANE PHOSPHOLIPIDS; TREATMENT OF SEPSIS OR RHEUMATOID ARTHRITIS | ELI LILLY AND COMPANY | 2004-05-04 | — | — | US | disclosed |
| EP-1362850-A1 | OXIME ETHER COMPOUND AND AGRICULTURAL OR HORTICULTURAL BACTERICIDE | NIPPON SODA CO., LTD. (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1307461-A2 | SUBSTITUTED PYRROLE COMPOUNDS AND THEIR USE AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012249-A2 | SUBSTITUTED PYRROLE COMPOUNDS AND THEIR USE AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |
| US-4695634-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1987-09-22 | — | — | US | disclosed |
| US-4622406-A | CHEMICAL INTERMEDIATES, TRIMETHYLSILOXY COMPOUNDS | PFIZER INC. (US) | 1986-11-11 | — | — | US | disclosed |
| US-4562267-A | Intermediates of hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1985-12-31 | — | — | US | disclosed |
| US-4423233-A | ALPHA-HYDROXY CARBOXIMIDATE INTERMEDIATES | PFIZER INC. (US) | 1983-12-27 | — | — | US | disclosed |
| US-4381308-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-04-26 | — | — | US | disclosed |
| US-4332952-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1982-06-01 | — | — | US | disclosed |