Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3696016 | 0.88 | PDE4A (0.36) | TNKS2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9298398 | 0.82 | ALOX5 (0.42) | ALOX5PTGS2HMGCRHTR2APPARA | |
| SCHEMBL3699161 | 0.81 | GAA (0.32) | ALOX5PTGS2GAAMAPTTSHR | |
| SCHEMBL4240144 | 0.79 | — | — | |
| SCHEMBL721971 | 0.79 | ALOX5 (0.50) | ALOX5PTGS2HTR2APPARA | |
| SCHEMBL9444539 | 0.79 | ALOX5 (0.50) | ALOX5PTGS2HTR2APPARA | |
| SCHEMBL9640505 | 0.79 | ALOX5 (0.50) | ALOX5PTGS2HTR2APPARA | |
| SCHEMBL19304408 | 0.79 | ALOX5 (0.50) | ALOX5PTGS2HTR2APPARA | |
| SCHEMBL10044860 | 0.79 | CA2 (0.32) | POLB | |
| SCHEMBL8516248 | 0.78 | HMGCR (0.47) | ALOX5PTGS2HMGCRHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9039936-B2 | Thiophene derivative, method for producing same, and polymer of thiophene derivative | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-05-26 | — | — | US | disclosed |
| US-9039936-B2 | Thiophene derivative, method for producing same, and polymer of thiophene derivative | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-05-26 | — | — | US | disclosed |
| US-9039936-B2 | Thiophene derivative, method for producing same, and polymer of thiophene derivative | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-05-26 | — | — | US | disclosed |
| EP-2457909-A1 | THIOPHENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND POLYMER OF THIOPHENE DERIVATIVE | Tokyo Institute of Technology (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-20120119157-A1 | THIOPHENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND POLYMER OF THIOPHENE DERIVATIVE | KURARAY CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20120119157-A1 | THIOPHENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND POLYMER OF THIOPHENE DERIVATIVE | KURARAY CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20120119157-A1 | THIOPHENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND POLYMER OF THIOPHENE DERIVATIVE | KURARAY CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120119157-A1 | THIOPHENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND POLYMER OF THIOPHENE DERIVATIVE | TST, WEE2, WEE1 | TNKS2 1427/4885PDE4A 3957/4885PDE4B 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.