Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298398 | 0.88 | ALOX5 (0.42) | HMGCRALOX5PTGS2HTR2AELANE | |
| SCHEMBL9444539 | 0.84 | ALOX5 (0.50) | ALOX5PTGS2HTR2A | |
| SCHEMBL721971 | 0.84 | ALOX5 (0.50) | ALOX5PTGS2HTR2A | |
| SCHEMBL9640505 | 0.84 | ALOX5 (0.50) | ALOX5PTGS2HTR2A | |
| SCHEMBL19304408 | 0.84 | ALOX5 (0.50) | ALOX5PTGS2HTR2A | |
| SCHEMBL9298002 | 0.82 | — | — | |
| SCHEMBL25644462 | 0.81 | GABRA1 (0.33) | HMGCRALDH1A1GABRA1GABRB2 | |
| SCHEMBL3703023 | 0.81 | HTR2A (0.32) | TAAR1HTR2AHTR2C | |
| SCHEMBL7265497 | 0.78 | HMGCR (0.33) | HMGCR | |
| SCHEMBL3700645 | 0.78 | TNKS2 (0.43) | HMGCRALOX5PTGS2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457909-A1 | THIOPHENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND POLYMER OF THIOPHENE DERIVATIVE | Tokyo Institute of Technology (JP) | 2012-05-30 | — | — | EP | disclosed |