Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463902 | 0.87 | P2RX7 (0.35) | KCNH2 | |
| SCHEMBL4185595 | 0.87 | ALDH1A1 (0.35) | SCN9AKCNH2SCN5A | |
| SCHEMBL1385654 | 0.87 | ALDH1A1 (0.35) | SCN9AKCNH2SCN5A | |
| SCHEMBL4181329 | 0.87 | ALDH1A1 (0.35) | SCN9AKCNH2SCN5A | |
| SCHEMBL4240395 | 0.84 | — | — | |
| SCHEMBL4466189 | 0.84 | TOP1 (0.36) | SCN9AKCNH2SCN5A | |
| SCHEMBL4464870 | 0.83 | RORC (0.31) | — | |
| SCHEMBL4464877 | 0.83 | RORC (0.31) | — | |
| SCHEMBL4467263 | 0.83 | RORC (0.31) | — | |
| SCHEMBL4478396 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531569-B2 | Process for preparing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-05-12 | — | — | US | claimed |