Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31178159 | 0.79 | TDO2 (0.46) | MAPK1NPC1TDO2KDM4EALDH1A1 | |
| SCHEMBL28300532 | 0.78 | MAPK1 (0.50) | MAPK1NPC1TDO2KDM4EALDH1A1 | |
| SCHEMBL2172244 | 0.77 | MAPK1 (0.49) | MAPK1NPC1TDO2KDM4EALDH1A1 | |
| SCHEMBL29543738 | 0.77 | MAPK1 (0.49) | MAPK1NPC1TDO2KDM4EALDH1A1 | |
| SCHEMBL2592400 | 0.77 | MAPK1 (0.49) | MAPK1NPC1TDO2KDM4EALDH1A1 | |
| SCHEMBL4341886 | 0.77 | MAPK1 (0.67) | MAPK1NPC1TDO2KDM4EALDH1A1 | |
| SCHEMBL21486436 | 0.77 | MAPK1 (0.45) | MAPK1NPC1TDO2KDM4EALDH1A1 | |
| SCHEMBL1531523 | 0.76 | MAPK1 (0.56) | MAPK1NPC1TDO2KDM4EALDH1A1 | |
| SCHEMBL18284817 | 0.76 | NOTUM (0.43) | NOS3NOS1NOS2NOTUMNAPRT | |
| SCHEMBL4235901 | 0.76 | NPC1 (0.47) | MAPK1NPC1TDO2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1140449-A | N-pyrazolyl anilines and N-pyrazolyl aminopyridines as pesticides | BAYER AG (DE) | 1997-01-15 | — | — | CN | claimed |
| CN-102834390-B | Diazinylpyrazolyl compounds | BAYER CROPSCIENCE AG | 2014-11-12 | — | — | CN | disclosed |
| CN-104066730-A | Heterocyclic compounds and their use as type III receptor tyrosine kinase modulators | AMBIT BIOSCIENCES CORP | 2014-09-24 | — | — | CN | disclosed |
| US-8507530-B2 | Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| CN-101611030-A | Pyrimidinylpyrazole as insecticide and parasiticide active agents | BAYER CROPSCIENCE AG (DE) | 2009-12-23 | — | — | CN | disclosed |
| US-20090082403-A1 | PYRIDINE DERIVATIVES SUBSTITUTED BY HETEROCYCLIC RING AND PHOSPHONOAMINO GROUP, AND ANTI-FUNGAL AGENT CONTAINING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-03-26 | — | — | US | disclosed |
| CN-1140449-A | N-pyrazolyl anilines and N-pyrazolyl aminopyridines as pesticides | BAYER AG (DE) | 1997-01-15 | — | — | CN | disclosed |
| CN-1140449-A | N-pyrazolyl anilines and N-pyrazolyl aminopyridines as pesticides | BAYER AG (DE) | 1997-01-15 | — | — | CN | disclosed |
| CN-1140449-A | N-pyrazolyl anilines and N-pyrazolyl aminopyridines as pesticides | BAYER AG (DE) | 1997-01-15 | — | — | CN | disclosed |
| EP-0745067-A1 | N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES | BAYER AG (DE) | 1996-12-04 | — | — | EP | disclosed |
| WO-1995022530-A1 | N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082403-A1 | PYRIDINE DERIVATIVES SUBSTITUTED BY HETEROCYCLIC RING AND PHOSPHONOAMINO GROUP, AND ANTI-FUNGAL AGENT CONTAINING SAME | ERG28, H1-2, H1-3 | MAPK1 19/4885NPC1 1237/4885TDO2 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.