Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785939 | 0.83 | CA2 (0.50) | MEN1GAAKMT2APTGS2PTGS1 | |
| SCHEMBL4243294 | 0.77 | PTGS2 (0.50) | KMT2APTGS2PTGS1LMNACYP2C9 | |
| SCHEMBL4601883 | 0.77 | PTGS2 (0.50) | KMT2APTGS2PTGS1LMNACYP2C9 | |
| SCHEMBL11438957 | 0.76 | PTGS2 (0.62) | KMT2APTGS2PTGS1LMNACYP2C9 | |
| SCHEMBL8474869 | 0.76 | CA12 (0.60) | MEN1GAAKMT2AIDO1CA1 | |
| SCHEMBL22996123 | 0.74 | SMN1; SMN2 (0.54) | MEN1GAAKMT2ALMNACYP2C9 | |
| SCHEMBL7433388 | 0.72 | PTGS2 (0.57) | PTGS2PTGS1LMNACYP2C9AKR1C3 | |
| SCHEMBL1250535 | 0.72 | PTGS2 (0.53) | PTGS2PTGS1LMNACYP2C9AKR1C3 | |
| SCHEMBL4480174 | 0.72 | FAAH (0.51) | PTGS2PTGS1LMNACYP2C9AKR1C3 | |
| SCHEMBL4474658 | 0.72 | FAAH (0.51) | PTGS2PTGS1LMNACYP2C9AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354392-B2 | Drug-introduced photo-crosslinked hyaluronic acid derived gel | SEIKAGAKU CORPORATION (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20090118348-A1 | DRUG-INTRODUCED PHOTO-CROSSLINKED HYALURONIC ACID DERIVED GEL | SEIKAGAKU CORPORATION (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-1905456-A1 | DRUG-CONTAINING PHOTOCROSSLINKED HYALURONIC ACID DERIVATIVE GEL | SEIKAGAKU CORPORATION (JP) | 2008-04-02 | — | — | EP | disclosed |