Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296982 | 0.84 | SMN1; SMN2 (0.61) | KMT2ASMN1; SMN2CACNA1GPOLBRAB9A | |
| SCHEMBL23497870 | 0.83 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2CACNA1GPOLBRAB9A | |
| SCHEMBL16176685 | 0.80 | CACNA1H (0.51) | KMT2ASMN1; SMN2CACNA1GPOLBRAB9A | |
| SCHEMBL23459074 | 0.80 | PIN1 (0.46) | KMT2ASMN1; SMN2CACNA1GPOLBRAB9A | |
| SCHEMBL13991771 | 0.79 | GAA (0.64) | KMT2ASMN1; SMN2POLBRAB9ATSHR | |
| SCHEMBL305355 | 0.79 | POLB (0.64) | KMT2ASMN1; SMN2POLBRAB9ATSHR | |
| SCHEMBL22775612 | 0.79 | MAPT (0.59) | KMT2ASMN1; SMN2POLBRAB9AMAPT | |
| SCHEMBL5897142 | 0.78 | KMT2A (0.57) | KMT2ASMN1; SMN2CACNA1GTSHRCACNA1H | |
| Hydrochloric Acid SCHEMBL27826900 | 0.78 | POLB (0.63) | KMT2ASMN1; SMN2POLBRAB9ATSHR | |
| SCHEMBL10447405 | 0.78 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2CACNA1GPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048252-A1 | THIAZOLONES FOR USE AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2009-02-19 | — | — | US | disclosed |
| US-20070249599-A1 | Novel Chemical Compounds | DUFFY KEVIN J | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249599-A1 | Novel Chemical Compounds | HIPK3, HIPK1, HIPK4 | KMT2A 2981/4885SMN1; SMN2 2249/4885CACNA1G 4799/4885 |
| US-20090048252-A1 | THIAZOLONES FOR USE AS PI3 KINASE INHIBITORS | PIK3CA, BTK, PI4KA | KMT2A 3096/4885SMN1; SMN2 2523/4885CACNA1G 2608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.