Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | BID | P55957 | 3/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.30 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.30 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.30 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6276311 | 0.93 | CA12 (0.31) | NR1H2NR1H3CA2SMN1; SMN2CA12 | |
| SCHEMBL4240875 | 0.84 | CA2 (0.36) | NR1H2NR1H3CA2SMN1; SMN2CA12 | |
| SCHEMBL6276316 | 0.80 | CA2 (0.33) | CA2CA12CA1CA9CYP2C9 | |
| SCHEMBL6051175 | 0.79 | CA2 (0.33) | CA2SMN1; SMN2CA12CA1CA9 | |
| SCHEMBL5516734 | 0.78 | LMNA (0.33) | — | |
| SCHEMBL6051181 | 0.77 | CA2 (0.33) | CA2SMN1; SMN2CA12CA1CA9 | |
| SCHEMBL5516742 | 0.76 | LMNA (0.35) | — | |
| SCHEMBL3746652 | 0.74 | NR1H2 (0.30) | NR1H2NR1H3 | |
| SCHEMBL3746661 | 0.74 | NR1H2 (0.30) | NR1H2NR1H3 | |
| SCHEMBL30140890 | 0.71 | CA2 (0.49) | CA2SMN1; SMN2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658076-A4 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1658076-A1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005020999-A1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |
| WO-2005003064-A2 | SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-13 | — | — | WO | disclosed |