SCHEMBL5516742

SCHEMBL5516742

CCCc1c(S(N)(=O)=O)ccc(C)c1N1CC=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5516734 0.91 LMNA (0.33) LMNAL3MBTL1
SCHEMBL6276316 0.84 CA2 (0.33)
SCHEMBL6051181 0.81 CA2 (0.33) LMNAGAA
SCHEMBL4240875 0.80 CA2 (0.36)
SCHEMBL6276311 0.80 CA12 (0.31)
SCHEMBL6051175 0.77 CA2 (0.33) LMNAGAA
SCHEMBL4240871 0.76 NR1H2 (0.37)
SCHEMBL3746661 0.74 NR1H2 (0.30)
SCHEMBL3746652 0.72 NR1H2 (0.30)
SCHEMBL5507157 0.66 CA2 (0.46) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1850849-A2 METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON Coley Pharmaceutical Group, Inc. (US) 2007-11-07 EP disclosed
WO-2006091647-A2 METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON COLEY PHARMACEUTICAL GROUP, INC. (US) 2006-08-31 WO disclosed