SCHEMBL424097

SCHEMBL424097

NC(=O)c1cccc(O)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.67
ALDH1A1 P00352 4/20 0.67
HPGD P15428 3/20 0.67
HSD17B10 Q99714 2/20 0.67
MAPT P10636 1/20 0.67
TSHR P16473 1/20 0.67
AKR1C3 P42330 1/20 0.53
AKR1C2 P52895 1/20 0.53
AKR1C1 Q04828 1/20 0.53
CA1 P00915 3/20 0.50
CA2 P00918 2/20 0.50
CA6 P23280 2/20 0.50
TERT O14746 2/20 0.50
MMP2 P08253 2/20 0.50
ALOX5 P09917 1/20 0.50
ADAMTS4 O75173 1/20 0.50
EGFR P00533 1/20 0.50
LMNA P02545 1/20 0.50
FYN P06241 1/20 0.50
MMP9 P14780 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29552052 1.00 KDM4E (0.67) KDM4EALDH1A1HPGDHSD17B10MAPT
Hydrochloric Acid SCHEMBL9377889 0.98 KDM4E (0.64) KDM4EALDH1A1HPGDHSD17B10MAPT
Ammonia Solution, Strong SCHEMBL8664317 0.98 KDM4E (0.64) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL698742 0.87 KDM4E (0.61) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL3723645 0.85 KDM4E (0.58) KDM4EALDH1A1HPGDHSD17B10MAPT
Octane SCHEMBL3330989 0.85 MAPT (0.54) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL924425 0.83 SELL (0.62) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL30211643 0.82 ERN1 (0.54) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL3424158 0.82 ERN1 (0.54) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL7063105 0.81 ALDH1A1 (0.50) KDM4EALDH1A1HPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4098650-B1 3-ALKOXY BENZOIC ACID AMIDE DERIVATIVE, AND PEST CONTROL AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2025-12-10 EP claimed
EP-4561985-B1 AMIDO-AMINE HARDENER JONES PAUL (GB) 2025-12-03 EP claimed
CN-117919213-A New application of N, 2-dihydroxybenzamide 中国农业科学院兰州畜牧与兽药研究所 2024-04-26 CN claimed
CN-116298043-A Screening method of inonotus obliquus active action quality markers and construction and application of chemical characterization map thereof 哈尔滨商业大学 2023-06-23 CN claimed
CN-113082025-B Application of dihydroxy benzamide derivative in preparation of SerC inhibitor and antituberculosis drug 上海市肺科医院 2023-01-20 CN claimed
CN-109876775-B Metal organic framework fiber material and preparation method thereof 中国石油化工股份有限公司 2022-04-08 CN claimed
CN-114144520-A Enhanced nucleic acid polymerization by aromatic compounds 斯特拉托斯基因公司 2022-03-04 CN claimed
US-20220008414-A1 PHARMACEUTICAL COMPOSITION COMPRISING HISTONE DEACETYLASE 6 INHIBITORS CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2022-01-13 US claimed
CN-113082025-A Application of dihydroxybenzamide derivatives in preparation of SerC inhibitor and antituberculosis drug 上海市肺科医院 2021-07-09 CN claimed
EP-3735409-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS Stratos Genomics Inc. (US) 2020-11-11 EP claimed
WO-2001030746-A1 METHOD FOR PREPARING A HYDROXYBENZONITRILE RHODIA CHIMIE (FR) 2001-05-03 WO claimed
US-5843618-A Hydrogen bond donating/accepting thermal solvents for image separation systems EASTMAN KODAK COMPANY (US) 1998-12-01 US claimed
US-5175024-A Removal of oxide layers by treatment with an amine and reduction with catechol compound AKZO N.V. (NL) 1992-12-29 US claimed
US-5140020-A Antiinflammatory agents KUREHA KAGATU KOGYO KABUSHIKI KAISHA (JP) 1992-08-18 US claimed
EP-0423163-A1 OXIDATIVE HAIR DYES Henkel Kommanditgesellschaft auf Aktien (DE) 1991-04-24 EP claimed
EP-0353452-A1 Oxidation hairdyeing composition Henkel Kommanditgesellschaft auf Aktien (DE) 1990-02-07 EP claimed
WO-1990000047-A1 OXIDATIVE HAIR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-01-11 WO claimed
US-4725598-A Derivative of dihydroxybenzamide and a pharmaceutical composition having an anti-inflammatory activity KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-02-16 US claimed
EP-0142241-B1 DIHYDROXYBENZAMIDE DERIVATIVES HAVING ANTI-INFLAMMATORY ACTIVITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-12-02 EP claimed
EP-0142241-A1 Dihydroxybenzamide derivatives having anti-inflammatory activity KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-05-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220008414-A1 PHARMACEUTICAL COMPOSITION COMPRISING HISTONE DEACETYLASE 6 INHIBITORS HDAC6, HDAC1, HDAC3 KDM4E 1264/4885ALDH1A1 1577/4885HPGD 973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.