Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 5/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723645 | 0.97 | KDM4E (0.58) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2174138 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL424097 | 0.87 | KDM4E (0.67) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29552052 | 0.87 | KDM4E (0.67) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2019650 | 0.85 | MMP2 (0.69) | KDM4EALDH1A1MAPTHPGDTSHR | |
| Ammonia Solution, Strong SCHEMBL8664317 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1MAPTHPGDTSHR | |
| Hydrochloric Acid SCHEMBL9377889 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL7332953 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL11651879 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDTSHR | |
| Cresotamide SCHEMBL1806785 | 0.84 | ALDH1A1 (0.67) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115287056-B | Preparation and application of natural annular molecular efficient fluorescence sensor | 青岛大学 | 2024-06-11 | — | — | CN | claimed |
| CN-116903581-A | SHP2/HDAC double-target inhibitor and preparation method and application thereof | 山东大学 | 2023-10-20 | — | — | CN | claimed |
| CN-115521228-B | BChE and HDAC double-target inhibitor and preparation method and application thereof | 中国药科大学 | 2023-08-22 | — | — | CN | claimed |
| CN-115521228-A | BChE and HDAC double-target inhibitor and preparation method and application thereof | 中国药科大学 | 2022-12-27 | — | — | CN | claimed |
| CN-115287056-A | Preparation and application of natural annular molecule efficient fluorescence sensor | 青岛大学 | 2022-11-04 | — | — | CN | claimed |
| EP-2217928-A2 | ALTERNATE LABELING STRATEGIES FOR SINGLE MOLECULE SEQUENCING | Pacific Biosciences of California, Inc. (US) | 2010-08-18 | — | — | EP | claimed |
| US-20090208957-A1 | Alternate labeling strategies for single molecule sequencing | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-08-20 | — | — | US | claimed |
| WO-2009073201-A2 | ALTERNATE LABELING STRATEGIES FOR SINGLE MOLECULE SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-06-11 | — | — | WO | claimed |
| EP-1792185-A2 | LANTHANIDE-BASED SUBSTRATES AND METHODS FOR DETERMINING CLOSTRIDIAL TOXIN ACTIVITY | Allergan, Inc. (US) | 2007-06-06 | — | — | EP | claimed |
| WO-2006033843-A2 | LANTHANIDE-BASED SUBSTRATES AND METHODS FOR DETERMINING CLOSTRIDIAL TOXIN ACTIVITY | ALLERGAN, INC. (US) | 2006-03-30 | — | — | WO | claimed |
| US-20060063221-A1 | Lanthanide-based substrates and methods for determining clostridial toxin activity | ALLERGAN, INC. | 2006-03-23 | — | — | US | claimed |
| CN-116283955-B | Compound for targeted degradation of HDAC7, and preparation method and application thereof | 浙江大学 | 2025-06-17 | — | — | CN | disclosed |
| US-20250084303-A1 | Complexes and Ligands | THE GENERAL HOSPITAL CORPORATION | 2025-03-13 | — | — | US | disclosed |
| US-12134721-B2 | Complexes and ligands | THE GENERAL HOSPITAL CORPORATION (US) | 2024-11-05 | — | — | US | disclosed |
| EP-4424686-A1 | COMPLEXES AND LIGANDS | The General Hospital Corporation (US) | 2024-09-04 | — | — | EP | disclosed |
| EP-1154990-A1 | PHTHALAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000048990-A1 | PHTHALAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-24 | — | — | WO | disclosed |
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0387106-A1 | Novel diamine compounds, production of the same and polyamideimide resins produced therefrom | TOMOEGAWA PAPER CO. LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084303-A1 | Complexes and Ligands | BID, CLTB, NECTIN4 | KDM4E 4822/4885ALDH1A1 3131/4885MAPT 2617/4885 |
| US-12134721-B2 | Complexes and ligands | BID, CLTB, NECTIN4 | KDM4E 4822/4885ALDH1A1 3131/4885MAPT 2617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.