Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 5/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698742 | 0.97 | KDM4E (0.61) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2174138 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL424097 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29552052 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2019650 | 0.83 | MMP2 (0.69) | KDM4EALDH1A1MAPTHPGDTSHR | |
| Ammonia Solution, Strong SCHEMBL8664317 | 0.83 | KDM4E (0.64) | KDM4EALDH1A1MAPTHPGDTSHR | |
| Hydrochloric Acid SCHEMBL9377889 | 0.83 | KDM4E (0.64) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL7332953 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL11651879 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL9656676 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129929-A1 | SELECTIVE PROTEIN LABELING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-11-11 | — | — | WO | disclosed |