SCHEMBL4240972

SCHEMBL4240972

C[Si]1(C)COc2c(C(=O)O)sc(C(=O)O)c2OC1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
GPR35 Q9HC97 2/20 0.32
POLB P06746 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8539380 0.76 ALDH1A1 (0.34) ALDH1A1HPGDTSHRGPR35POLB
SCHEMBL1720848 0.76 BAZ2B (0.35) ALDH1A1HPGDTSHRGPR35POLB
SCHEMBL28343182 0.74 BAZ2B (0.34) ALDH1A1HPGDTSHRGPR35POLB
Water SCHEMBL6834330 0.74 XDH (0.35) ALDH1A1HPGDTSHRGPR35POLB
SCHEMBL4984511 0.69 GPR35 (0.31) ALDH1A1HPGDTSHRGPR35
SCHEMBL421643 0.68 ALDH1A1 (0.31) ALDH1A1HPGDTSHR
SCHEMBL5730433 0.68
SCHEMBL5037638 0.67 POLB (0.30) ALDH1A1HPGDTSHRPOLBCTDSP1
SCHEMBL8539138 0.65 KMT2A (0.44) ALDH1A1HPGDTSHRPOLB
SCHEMBL420112 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080055701-A1 SWITCHABLE WINDOW BASED ON ELECTROCHROMIC POLYMERS UNIVERSITY OF WASHINGTON (US) 2008-03-06 US claimed
US-7547658-B2 Switchable window based on electrochromic polymers UNIVERSITY OF WASHINGTON (US) 2009-06-16 US disclosed
US-7505191-B2 Electrochromic monomers and polymers for a switchable window UNIVERSITY OF WASHINGTON (US) 2009-03-17 US disclosed
US-20080055701-A1 SWITCHABLE WINDOW BASED ON ELECTROCHROMIC POLYMERS UNIVERSITY OF WASHINGTON (US) 2008-03-06 US disclosed
US-20070268550-A1 SWITCHABLE WINDOW BASED ON ELECTROCHROMIC POLYMERS UNIVERSITY OF WASHINGTON (US) 2007-11-22 US disclosed
US-7256923-B2 Switchable window based on electrochromic polymers UNIVERSITY OF WASHINGTON (US) 2007-08-14 US disclosed
US-20050200935-A1 Switchable window based on electrochromic polymers UNIVERSITY OF WASHINGTON (US) 2005-09-15 US disclosed