Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983142 | 0.94 | NPC1 (0.65) | TACR2TDP1NPC1RAB9APDCD1 | |
| SCHEMBL2699064 | 0.90 | ALDH1A1 (0.66) | TACR2TDP1NPC1RAB9APDCD1 | |
| SCHEMBL3397230 | 0.90 | PDCD1 (0.67) | TACR2TDP1NPC1RAB9APDCD1 | |
| SCHEMBL12335182 | 0.90 | TACR2 (0.60) | TACR2TDP1NPC1RAB9APDCD1 | |
| SCHEMBL2463491 | 0.89 | NPC1 (0.63) | TACR2TDP1NPC1RAB9APDCD1 | |
| SCHEMBL2556112 | 0.88 | TACR2 (0.76) | TACR2TDP1NPC1RAB9APDCD1 | |
| SCHEMBL13220784 | 0.85 | TACR2 (1.00) | TACR2TDP1NPC1RAB9APDCD1 | |
| SCHEMBL22291225 | 0.85 | L3MBTL1 (0.58) | TACR2TDP1NPC1RAB9APDCD1 | |
| SCHEMBL662145 | 0.85 | TACR2 (0.75) | TACR2TDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL1609108 | 0.85 | TACR2 (0.75) | TACR2TDP1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507523-A4 | CINNAMIC ACID DIMERS, THEIR PREPARATION AND THE USE THEREOF FOR TREATING NEURODEGENERATIVE DISEASE | KOREA INST SCI & TECH (KR) | 2009-07-15 | — | — | EP | disclosed |
| EP-1507523-A1 | CINNAMIC ACID DIMERS, THEIR PREPARATION AND THE USE THEREOF FOR TREATING NEURODEGENERATIVE DISEASE | Korea Institute of Science and Technology (KR) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003099269-A1 | CINNAMIC ACID DIMERS, THEIR PREPARATION AND THE USE THEREOF FOR TREATING NEURODEGENERATIVE DISEASE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-12-04 | — | — | WO | disclosed |