Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | TACR2 | P21452 | 1/20 | 0.64 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.61 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | FDPS | P14324 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397230 | 0.95 | PDCD1 (0.67) | NPC1RAB9ATDP1TACR2PDCD1 | |
| SCHEMBL2699064 | 0.95 | ALDH1A1 (0.66) | NPC1RAB9ATDP1TACR2PDCD1 | |
| SCHEMBL2463491 | 0.94 | NPC1 (0.63) | NPC1RAB9ATDP1TACR2PDCD1 | |
| SCHEMBL4241206 | 0.94 | TACR2 (0.74) | NPC1RAB9ATDP1TACR2PDCD1 | |
| SCHEMBL2556112 | 0.93 | TACR2 (0.76) | NPC1RAB9ATDP1TACR2PDCD1 | |
| SCHEMBL12335182 | 0.92 | TACR2 (0.60) | NPC1RAB9ATDP1TACR2PDCD1 | |
| SCHEMBL7784719 | 0.89 | PDCD1 (0.74) | NPC1RAB9ATDP1TACR2PDCD1 | |
| SCHEMBL22160281 | 0.88 | NPC1 (0.62) | NPC1RAB9ATDP1TACR2PDCD1 | |
| SCHEMBL24707029 | 0.88 | NPC1 (0.55) | NPC1RAB9ATDP1TACR2PDCD1 | |
| SCHEMBL988304 | 0.87 | RAB9A (0.60) | NPC1RAB9ATDP1TACR2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024136462-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, IMPROVING OR TREATING ATOPY COMPRISING FLAVONOID DERIVATIVE AS ACTIVE INGREDIENT AND METHOD FOR PREPARING FLAVONOID DERIVATIVE | LEEYUN BIO CO.,LTD. (KR) | 2024-06-27 | — | — | WO | disclosed |
| EP-2706062-B1 | NOVEL CEPHALOSPORIN DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | LEGOCHEM BIOSCIENCES INC (KR) | 2018-05-09 | — | — | EP | disclosed |
| US-9630977-B2 | Cephalosporin derivatives and pharmaceutical compositions thereof | LEGOCHEM BIOSCIENCES, INC. (KR) | 2017-04-25 | — | — | US | disclosed |
| EP-2706062-A2 | NOVEL CEPHALOSPORIN DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | LegoChem Biosciences, Inc. (KR) | 2014-03-12 | — | — | EP | disclosed |
| EP-2706062-A2 | NOVEL CEPHALOSPORIN DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | LegoChem Biosciences, Inc. (KR) | 2014-03-12 | — | — | EP | disclosed |
| US-20130178455-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCES, INC (US) | 2013-07-11 | — | — | US | disclosed |
| US-8329684-B2 | Cephalosporin derivatives and pharmaceutical compositions thereof | LEGOCHEM BIOSCIENCES, INC. (KR) | 2012-12-11 | — | — | US | disclosed |
| US-8329684-B2 | Cephalosporin derivatives and pharmaceutical compositions thereof | LEGOCHEM BIOSCIENCES, INC. (KR) | 2012-12-11 | — | — | US | disclosed |
| US-20120264727-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCES, INC. (KR) | 2012-10-18 | — | — | US | disclosed |
| US-20120264727-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCES, INC. (KR) | 2012-10-18 | — | — | US | disclosed |
| WO-2012134184-A2 | NOVEL CEPHALOSPORIN DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME | 주식회사 레고켐 바이오사이언스 (KR) | 2012-10-04 | — | — | WO | disclosed |
| EP-0409164-B1 | Phenacylpyridiniothiocephalosporins | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5134138-A | ANTIBIOTICS | SHIONOGI & CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0409164-A2 | Phenacylpyridiniothiocephalosporins | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4568490-A | REDUCTIVE CONDENSATION WITH A CARBONYL COMPOUND | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1986-02-04 | — | — | US | disclosed |
| US-4537880-A | Aminopropylaminobleomycin derivatives and process for preparation thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178455-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | CSDE1, CELA1, ABCC1 | NPC1 1325/4885RAB9A 2175/4885TDP1 2466/4885 |
| US-20120264727-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | CSDE1, CELA1, ABCC1 | NPC1 1325/4885RAB9A 2175/4885TDP1 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.