Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 6/20 | 0.73 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | NQO2 | P16083 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16711721 | 0.87 | KDM4E (0.74) | MTNR1BMTNR1AMEN1KMT2APOLB | |
| SCHEMBL16926284 | 0.86 | ALDH1A1 (0.61) | MTNR1BMTNR1APOLBNQO2CYP1A2 | |
| SCHEMBL6575505 | 0.86 | MTNR1A (0.55) | MTNR1BMTNR1AMAPTMEN1KMT2A | |
| SCHEMBL16711696 | 0.86 | NQO2 (0.76) | MTNR1BMTNR1AMAPTMEN1KMT2A | |
| SCHEMBL16716153 | 0.85 | ALDH1A1 (0.60) | MTNR1BMTNR1APOLBNQO2CYP1A2 | |
| SCHEMBL16716169 | 0.85 | ALDH1A1 (0.60) | MTNR1BMTNR1APOLBNQO2CYP1A2 | |
| SCHEMBL8946916 | 0.85 | MTNR1A (1.00) | MTNR1BMTNR1AMAPTMEN1KMT2A | |
| SCHEMBL31543713 | 0.85 | MTNR1A (1.00) | MTNR1BMTNR1AMAPTMEN1KMT2A | |
| SCHEMBL16926301 | 0.84 | ALDH1A1 (0.59) | MTNR1BMTNR1APOLBNQO2CYP1A2 | |
| SCHEMBL1343728 | 0.83 | KDM4E (0.66) | MTNR1BMTNR1AMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090252678-A1 | COX-2-TARGETED IMAGING AGENTS | VANDERBILT UNIVERSITY (US) | 2009-10-08 | — | — | US | disclosed |
| US-20050002859-A1 | COX-2-targeted imaging agents | VANDERBILT UNIVERSITY (US) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050002859-A1 | COX-2-targeted imaging agents | PTGS2, PTGES2, PTGER2 | MTNR1B 338/4885MTNR1A 327/4885MAPT 2270/4885 |
| US-20090252678-A1 | COX-2-TARGETED IMAGING AGENTS | PTGS2, PTGES2, PTGER2 | MTNR1B 338/4885MTNR1A 327/4885MAPT 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.