SCHEMBL424271

SCHEMBL424271

CC(C)(C)c1cccc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.52
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
LMNA P02545 1/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
POLB P06746 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALOX12 P18054 1/20 0.39
KDM4E B2RXH2 3/20 0.37
HPGD P15428 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
RBP4 P02753 1/20 0.35
MEN1 O00255 1/20 0.35
APAF1 O14727 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29501855 1.00 CA2 (0.52) CA2GABRA1GABRB2NPC1RAB9A
Acetic Acid SCHEMBL2229999 0.93 CA2 (0.44) CA2GABRA1GABRB2NPC1RAB9A
SCHEMBL8024417 0.89 CA2 (0.41) CA2GABRA1GABRB2NPC1RAB9A
Propionic Acid SCHEMBL5630265 0.89 CA2 (0.41) CA2GABRA1GABRB2NPC1RAB9A
SCHEMBL29040997 0.87 NPC1 (0.45) CA2GABRA1GABRB2NPC1RAB9A
SCHEMBL20272359 0.84 NPC1 (0.41) CA2NPC1RAB9ALMNAATM
SCHEMBL29904482 0.84 NPC1 (0.41) CA2NPC1RAB9ALMNAATM
SCHEMBL2231426 0.84 NPC1 (0.41) CA2GABRA1GABRB2NPC1RAB9A
SCHEMBL1767326 0.84 CA2 (0.42) CA2GABRA1GABRB2NPC1RAB9A
SCHEMBL30426108 0.84 CA2 (0.42) CA2GABRA1GABRB2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2679616-B1 Ultraviolet radiation absorbing polyethers JOHNSON & JOHNSON CONSUMER INC (US) 2018-05-16 EP claimed
EP-2866898-B1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER INC (US) 2018-04-04 EP claimed
EP-2866783-B1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC (US) 2018-01-10 EP claimed
EP-2866899-B1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC (US) 2017-12-27 EP claimed
US-20170312203-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC. (US) 2017-11-02 US claimed
US-20170304174-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC. (US) 2017-10-26 US claimed
US-9737471-B2 Sunscreen compositions containing an ultraviolet radiation-absorbing polymer JOHNSON & JOHNSON CONSUMER INC. (US) 2017-08-22 US claimed
US-9737470-B2 Sunscreen compositions containing an ultraviolet radiation-absorbing polymer JOHNSON & JOHNSON CONSUMER INC. (US) 2017-08-22 US claimed
US-20170198076-A1 CURABLE COMPOSITION AND POLYMER MITSUBISHI RAYON CO., LTD. (JP) 2017-07-13 US claimed
US-9663603-B2 Curable composition and polymer MITSUBISHI RAYON CO., LTD. (JP) 2017-05-30 US claimed
EP-2866898-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS Johnson & Johnson Consumer Companies, Inc. (US) 2015-05-06 EP claimed
EP-2866899-A2 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER Johnson & Johnson Consumer Companies, Inc. (US) 2015-05-06 EP claimed
EP-2866783-A2 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER Johnson & Johnson Consumer Companies, Inc. (US) 2015-05-06 EP claimed
WO-2014004474-A2 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO claimed
WO-2014004176-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO claimed
WO-2014004477-A2 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO claimed
US-20140004064-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER KENVUE BRANDS LLC 2014-01-02 US claimed
US-20140004061-A1 ULTRAVIOLET RADIATION ABSORBING POLYETHERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-02 US claimed
US-20140004060-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-02 US claimed
US-20140004063-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170304174-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER PCNA, SUN2, TTPA CA2 4863/4885GABRA1 2100/4885GABRB2 1739/4885
US-20140004061-A1 ULTRAVIOLET RADIATION ABSORBING POLYETHERS ERCC4, XRCC6, PUF60 CA2 4757/4885GABRA1 1318/4885GABRB2 1268/4885
US-20140004060-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS PARG, PARN, PUF60 CA2 4443/4885GABRA1 1833/4885GABRB2 1719/4885
US-20170312203-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER MMS19, SUN2, ERCC1 CA2 4707/4885GABRA1 3633/4885GABRB2 3275/4885
US-20140004064-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER PCNA, SUN2, TTPA CA2 4863/4885GABRA1 2100/4885GABRB2 1739/4885
US-20140004063-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER MMS19, SUN2, ERCC1 CA2 4707/4885GABRA1 3633/4885GABRB2 3275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.