Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 8/20 | 0.39 |
| ▸ | DRD1 | P21728 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646170 | 0.79 | ACHE (0.60) | ACHENQO2MTNR1AMTNR1BKDM4E | |
| SCHEMBL16624111 | 0.78 | HTR2C (0.39) | ACHENQO2MTNR1AMTNR1BKDM4E | |
| SCHEMBL4251083 | 0.78 | ACHE (0.46) | ACHENQO2MTNR1AMTNR1BKDM4E | |
| SCHEMBL19236330 | 0.77 | DRD3 (0.32) | ACHEDRD2ADRA1ADRD3 | |
| SCHEMBL18034949 | 0.77 | ALDH1A1 (0.41) | ACHENQO2MTNR1AMTNR1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL17965629 | 0.77 | HTR2C (0.38) | ACHENQO2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL22837453 | 0.77 | HTR2A (0.47) | MTNR1AMTNR1BDRD2DRD3 | |
| SCHEMBL7542801 | 0.77 | HTR2A (0.47) | MTNR1AMTNR1BDRD2DRD3 | |
| Arsenic SCHEMBL5712628 | 0.76 | ACHE (0.45) | ACHENQO2MTNR1AMTNR1BKDM4E | |
| Ammonia Solution, Strong SCHEMBL5712534 | 0.76 | ACHE (0.45) | ACHENQO2MTNR1AMTNR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076325-B2 | 1,2,4,5-tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2011-12-13 | — | — | US | disclosed |
| US-20090069296-A1 | 1,2,4,5-Tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069296-A1 | 1,2,4,5-Tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them | OXER1, NR1H3, OXSR1 | ACHE 2167/4885NQO2 1600/4885MTNR1A 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.