SCHEMBL8646170

SCHEMBL8646170

COc1ccc2c(c1OC)C(C)C2

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.60
NQO2 P16083 1/20 0.43
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
ATM Q13315 1/20 0.41
DRD2 P14416 4/20 0.40
DRD1 P21728 2/20 0.40
KCNH2 Q12809 1/20 0.39
ADRA1A P35348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7332638 0.87 ACHE (0.51) ACHENQO2MTNR1AMTNR1BDRD2
SCHEMBL7337498 0.80 DRD2 (0.47) ACHENQO2MTNR1AMTNR1BDRD2
SCHEMBL4251083 0.79 ACHE (0.46) ACHENQO2MTNR1AMTNR1BKDM4E
SCHEMBL4243156 0.79 ACHE (0.46) ACHENQO2MTNR1AMTNR1BKDM4E
Hydrochloric Acid SCHEMBL7339332 0.79 DRD2 (0.46) ACHENQO2MTNR1AMTNR1BDRD2
Ammonia Solution, Strong SCHEMBL5712534 0.78 ACHE (0.45) ACHENQO2MTNR1AMTNR1BKDM4E
Arsenic SCHEMBL5712628 0.78 ACHE (0.45) ACHENQO2MTNR1AMTNR1BKDM4E
SCHEMBL7339382 0.77 ACHE (0.45) ACHENQO2MTNR1AMTNR1BDRD2
SCHEMBL7339385 0.77 ACHE (0.45) ACHENQO2MTNR1AMTNR1BKDM4E
Bromide SCHEMBL5712634 0.77 ACHE (0.44) ACHENQO2MTNR1AMTNR1BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618237-B1 Polymerization process FUSION UV SYS INC (US) 1998-09-02 EP claimed