SCHEMBL4243799

SCHEMBL4243799

OC1=COc2cc(O)ccc2O1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.43
ESR2 Q92731 1/20 0.41
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
TYR P14679 2/20 0.33
FTO Q9C0B1 2/20 0.33
TRPA1 O75762 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
SMAD3 P84022 1/20 0.33
KMT2A Q03164 1/20 0.33
PRMT1 Q99873 1/20 0.33
ACE2 Q9BYF1 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KIT P10721 1/20 0.33
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4735618 0.76
SCHEMBL9255027 0.75 CA12 (0.45) CYP3A4ESR2MAPTMEN1HPGD
SCHEMBL7817781 0.75 CA12 (0.37) CYP3A4ESR2TYRMEN1HPGD
SCHEMBL10637475 0.75 MTNR1A (0.40) CYP3A4MAPTHPGDRECQLBLM
SCHEMBL9258029 0.70 DRD3 (0.37) CYP3A4ESR2KDM4EHSD17B10
SCHEMBL18417129 0.70 AHR (0.54) CYP3A4MAPTHTTTYRFTO
SCHEMBL14435757 0.70 CYP3A4 (0.48) CYP3A4MAPTTYRTRPA1MEN1
SCHEMBL9258041 0.68 CYP3A4 (0.32) CYP3A4ESR2RECQL
SCHEMBL8580093 0.68 CA12 (0.49) ESR2MAPTHTTMEN1HPGD
SCHEMBL9260062 0.67 CA12 (0.37) CYP3A4ESR2TYRMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7556902-B2 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2009-07-07 US disclosed
US-7348113-B2 Electrophotographic photoconductor comprising a polycarbonate resin having a dihydroxy diphenyl ether unit RICOH COMPANY, LTD. (JP) 2008-03-25 US disclosed
US-7122284-B2 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2006-10-17 US disclosed
US-7056633-B2 Electrophotographic photoconductor, image forming method and apparatus, and process cartidge using the photocondutor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2006-06-06 US disclosed
US-20060046169-A1 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2006-03-02 US disclosed
US-20060035161-A1 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2006-02-16 US disclosed
US-6974654-B2 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE USING THE PHOTOCONDUCTOR, AND LONG-CHAIN ALKYL GROUP CONTAINING BISPHENOL COMPOUND AND POLYMER MADE THEREFROM RICOH COMPANY, LTD. (JP) 2005-12-13 US disclosed
US-20050106483-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, dihydroxy diphenyl ether compound, and process of manufacturing dihydroxy diphenyl ether compound RICOH COMPANY, LTD. (JP) 2005-05-19 US disclosed
US-20040131960-A1 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2004-07-08 US disclosed
US-20030198881-A1 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2003-10-23 US disclosed
US-6548216-B2 Forming electrostatic latent images RICOH COMPANY, LTD. (JP) 2003-04-15 US disclosed
US-20020025483-A1 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2002-02-28 US disclosed
US-6018014-A PRESCRIBED DIOL MONOMER HAS STRUCTURE HYDROXY-(ARYLENE)-(2-(AMINOARYL OR HETEROCYCLE)VINYL)-(ARYLENE)-HYDROXYL;USEFUL FOR A CHARGE-TRANSPORT POLYMER MATERIAL FOR AN ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEDIUM RICOH COMPANY, LTD. (JP) 2000-01-25 US disclosed
US-5840454-A Aromatic polycarbonate and electrophotographic photosensitive medium using same RICOH COMPANY, LTD. (JP) 1998-11-24 US disclosed