Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262412 | 0.69 | NAAA (0.47) | TSHR | |
| SCHEMBL4243799 | 0.68 | CYP3A4 (0.43) | CYP3A4RECQLESR2 | |
| SCHEMBL8580093 | 0.68 | CA12 (0.49) | ESR2ESR1 | |
| SCHEMBL9258029 | 0.67 | DRD3 (0.37) | CYP3A4TSHRESR2DRD2DRD4 | |
| SCHEMBL9628427 | 0.67 | DRD3 (0.48) | CYP3A4TSHRESR2DRD2DRD4 | |
| SCHEMBL7098613 | 0.65 | MTNR1A (0.40) | — | |
| SCHEMBL9258362 | 0.65 | HPGD (0.43) | TSHRDRD3 | |
| SCHEMBL9255027 | 0.65 | CA12 (0.45) | CYP3A4ESR2ESR1 | |
| SCHEMBL4735618 | 0.62 | — | — | |
| SCHEMBL9251348 | 0.62 | CA12 (0.49) | TSHRESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |