Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237855 | 0.94 | NR1H2 (0.35) | NR1H2CSNK2A2CSNK2A1GAAPTPN11 | |
| SCHEMBL4298498 | 0.93 | FFAR1 (0.39) | FFAR1FFAR4MMP2MMP12NR1H2 | |
| SCHEMBL4237042 | 0.91 | NR1H2 (0.38) | NR1H2CSNK2A2CSNK2A1GAAPTPN11 | |
| SCHEMBL4231082 | 0.90 | NR1H2 (0.41) | NR1H2CSNK2A2CSNK2A1GAACNR2 | |
| SCHEMBL4057543 | 0.88 | NR1H2 (0.36) | NR1H2CSNK2A2CSNK2A1GAAL3MBTL1 | |
| SCHEMBL4238011 | 0.86 | NR1H2 (0.37) | NR1H2CSNK2A2CSNK2A1GAAL3MBTL1 | |
| SCHEMBL4294605 | 0.84 | PTPN11 (0.38) | NR1H2PTPN11 | |
| SCHEMBL4242529 | 0.84 | GABRG2 (0.38) | NR1H2CSNK2A2CSNK2A1GAAL3MBTL1 | |
| SCHEMBL4068204 | 0.83 | KDM4E (0.39) | FFAR1NR1H2GAAL3MBTL1MAPT | |
| SCHEMBL4056602 | 0.82 | FGFR3 (0.39) | NR1H2GAAL3MBTL1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |