Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063530 | 0.93 | KDM4E (0.38) | KDM4EHSD17B10NR1H2ACACBF2 | |
| SCHEMBL4231082 | 0.91 | NR1H2 (0.41) | NR1H2SMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL4235750 | 0.90 | KDM4E (0.44) | KDM4EHSD17B10F2ALOX15KMT2A | |
| SCHEMBL4296852 | 0.89 | FFAR1 (0.39) | NR1H2FFAR1KMT2APAX8EGFR | |
| SCHEMBL4231079 | 0.85 | ALDH1A1 (0.38) | KDM4EHSD17B10NR1H2SMN1; SMN2CYP1A2 | |
| SCHEMBL4241713 | 0.85 | FGFR3 (0.38) | KDM4EHSD17B10NR1H2SMN1; SMN2CYP1A2 | |
| SCHEMBL4057543 | 0.84 | NR1H2 (0.36) | KDM4ENR1H2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4237042 | 0.84 | NR1H2 (0.38) | KDM4ENR1H2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4238011 | 0.84 | NR1H2 (0.37) | NR1H2KMT2AALDH1A1TSHRGAA | |
| SCHEMBL4243989 | 0.83 | FFAR1 (0.36) | NR1H2FFAR1GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |