Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 4/20 | 0.49 |
| ▸ | MIF | P14174 | 2/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124996 | 0.84 | HTR2A (0.51) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| SCHEMBL12163330 | 0.84 | BCHE (0.44) | MEN1KMT2AHTR2BHTR2CKDM4E | |
| SCHEMBL11231510 | 0.83 | MEN1 (0.58) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| SCHEMBL4243270 | 0.81 | HTR2A (0.56) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| SCHEMBL22651831 | 0.81 | MEN1 (0.49) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| SCHEMBL46757 | 0.81 | HTR2A (0.63) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| SCHEMBL7766011 | 0.80 | HRH3 (0.56) | MEN1KMT2AHTR2BHTR2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL8390076 | 0.80 | IDO1 (0.54) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| SCHEMBL4239892 | 0.79 | MEN1 (0.85) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| SCHEMBL4567 | 0.79 | TAAR1 (0.60) | MEN1KMT2AHTR2AHTR2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4293009-B1 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | ZOGENIX INTERNATIONAL LTD (GB) | 2025-06-11 | — | — | EP | disclosed |
| EP-3800177-B1 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | ZOGENIX INTERNATIONAL LTD (GB) | 2025-01-29 | — | — | EP | disclosed |
| EP-4293009-A2 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | Zogenix International Limited (GB) | 2023-12-20 | — | — | EP | disclosed |
| US-11634377-B2 | Fenfluramine compositions and methods of preparing the same | ZOGENIX INTERNATIONAL LIMITED (GB) | 2023-04-25 | — | — | US | disclosed |
| US-20090137653-A1 | SUBSTITUTED BENZYLAMINES AS CYP2A INHIBITORS AND USES THEREOF TO TREAT NICOTINE DEPENDENCE | INFLAYZME PHARMACEUTICALS LTD. (CA) | 2009-05-28 | — | — | US | disclosed |
| EP-1871357-A2 | SUBSTITUTED BENZYLAMINES AS CYP2A INHIBITORS AND USES THEREOF TO TREAT NICOTINE DEPENDENCE | Inflazyme Pharmaceuticals, Ltd. (CA) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006108149-A2 | SUBSTITUTED BENZYLAMINES AS CYP2A INHIBITORS AND USES THEREOF TO TREAT NICOTINE DEPENDENCE | INFLAZYME PHARMACEUTICALS LTD. (CA) | 2006-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634377-B2 | Fenfluramine compositions and methods of preparing the same | FAAH, FAAH2, TPH1 | MEN1 2032/4885KMT2A 1462/4885HTR2A 34/4885 |
| US-20090137653-A1 | SUBSTITUTED BENZYLAMINES AS CYP2A INHIBITORS AND USES THEREOF TO TREAT NICOTINE DEPENDENCE | CYP2A6, CYP2B6, CYP2D6 | MEN1 4777/4885KMT2A 475/4885HTR2A 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.