SCHEMBL4244795

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4243829	0.89	CHEK2 (0.44)	CHEK2GPR119CSF1RKDRSCN9A
	SCHEMBL4241460	0.87	CHEK2 (0.46)	CHEK2GPR119CSF1RKDRALOX5AP
	SCHEMBL4061637	0.80	BRD4 (0.42)	SCN9A
	SCHEMBL4244345	0.78	TLR7 (0.53)	CHEK2GPR119
	SCHEMBL4245979	0.76	TLR7 (0.44)	CHEK2
	SCHEMBL27006794	0.75	GPR119 (0.52)	CHEK2GPR119CSF1RKDRSCN9A
	SCHEMBL4245395	0.74	TLR7 (0.41)	CHEK2
	SCHEMBL12252347	0.73	CHEK2 (0.59)	CHEK2GPR119CSF1RKDRPDE3B
	SCHEMBL4247610	0.72	TLR7 (0.40)	KDR
	SCHEMBL4140112	0.72	GPR119 (0.71)	CHEK2GPR119SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.