Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.51 |
| ▸ | RAB9A | P51151 | 14/20 | 0.51 |
| ▸ | MAPT | P10636 | 13/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244237 | 0.91 | SMN1; SMN2 (0.52) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL13744285 | 0.86 | BUB1 (0.40) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL4245920 | 0.85 | MEN1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL4238703 | 0.84 | NPC1 (0.41) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13743346 | 0.84 | NPC1 (0.53) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL4238314 | 0.84 | NPC1 (0.55) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL4242180 | 0.83 | MAPT (0.46) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL4245974 | 0.83 | DEGS1 (0.46) | ALDH1A1KLF5 | |
| SCHEMBL4243214 | 0.83 | KMT2A (0.45) | MAPTTP53KDM4EMAPK1KMT2A | |
| SCHEMBL4240480 | 0.82 | PORCN (0.44) | RAB9AMAPTSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | NPC1 163/4885RAB9A 2428/4885MAPT 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.