Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 16/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27294895 | 0.75 | KDM4E (0.46) | PRKCQKDM4EUSP2ALDH1A1 | |
| SCHEMBL4245343 | 0.72 | PRKCQ (0.42) | PRKCQPRKCDSMN1; SMN2 | |
| SCHEMBL8039491 | 0.72 | ALDH1A1 (0.59) | KDM4EUSP2ALDH1A1HPGDMAPK1 | |
| SCHEMBL642228 | 0.71 | HDAC4 (0.58) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL4696500 | 0.69 | ALDH1A1 (0.55) | KDM4EUSP2ALDH1A1 | |
| SCHEMBL5481379 | 0.69 | KDM4E (0.46) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL21922075 | 0.67 | CSNK1A1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL7336233 | 0.67 | KDM4E (0.52) | KDM4EUSP2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6968151 | 0.67 | KDM4E (0.52) | KDM4EUSP2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1256303 | 0.66 | PRKCZ (0.45) | PRKCQKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | WYETH | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K6 | PRKCQ 166/4885PRKCD 314/4885KDM4E 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.